Joao Lago | Pharmacology | Best Researcher Award Posted on 14/06/202415/08/2024 by sciencefatherLeave a Comment on Joao Lago | Pharmacology | Best Researcher Award Prof Dr. Joao Lago | Pharmacology | Best Researcher Award Professor at Federal University of ABC, Brazil Prof. Dr. Joao Henrique Ghilardi Lago is a distinguished researcher in Chemistry, specializing in the Chemistry of Natural Products. With extensive academic credentials including a Ph.D. from the University of São Paulo and a background in both chemical education and research, he has made significant contributions to the field. His current position at the Federal University of ABC reflects his commitment to teaching and research in biosystems and organic chemistry. 🌿🔬 Dr. Lago’s work is marked by his leadership in various research projects focusing on the characterization and potential applications of specialized metabolites from Brazilian flora, particularly in combating neglected tropical diseases. His role as a grantee and reviewer for multiple scientific funding agencies underscores his influence and expertise in the scientific community, contributing to the advancement of bioorganic chemistry and pharmaceutical research in Brazil and beyond. 🌍 Professional Profile: Google Scholar Education Prof. Dr. Joao Henrique Ghilardi Lago pursued a rigorous academic journey culminating in his esteemed position in the scientific community. He earned his Bachelor’s degree in Chemistry from the Federal University of Mato Grosso do Sul (UFMS), Brazil, before advancing to achieve a Master’s and Ph.D. in Chemistry from the University of São Paulo (USP), one of Brazil’s leading institutions. 🎓 His doctoral research focused on natural products chemistry, a field he has since dedicated himself to with passion and expertise. Througho ut his educational path, Dr. Lago has demonstrated a commitment to excellence in scientific inquiry and a deep understanding of organic chemistry principles. His academic background has equipped him with the skills and knowledge to lead impactful research initiatives, particularly in the chemistry of natural products and their potential applications in medicine and pharmacology. 🌿🔬 Professional Experience Prof. Dr. Joao Henrique Ghilardi Lago boasts a rich professional experience marked by significant contributions to the fields of chemistry and academia. He has held key positions such as a researcher and professor at the Federal University of Mato Grosso do Sul (UFMS), Brazil, where he has actively engaged in teaching and mentoring students while conducting groundbreaking research. 🌟 Dr. Lago’s research interests encompass natural products chemistry, medicinal chemistry, and synthetic organic chemistry, areas in which he has published numerous influential papers in prestigious scientific journals. His professional journey also includes collaborations with national and international research groups, fostering interdisciplinary approaches to tackle complex scientific challenges. As a recognized expert in his field, Dr. Lago continues to inspire and educate future generations of scientists through his dedicated work and leadership in academia. 🔍🔬 Research Interest Prof. Dr. Joao Henrique Ghilardi Lago’s research interests are centered around the fascinating realms of natural products chemistry, medicinal chemistry, and synthetic organic chemistry. 🌿 His work delves into the exploration and synthesis of bioactive compounds derived from natural sources, aiming to uncover their potential applications in medicine and related fields. Dr. Lago is particularly intrigued by the molecular structures of natural products and their intricate biological activities, seeking to elucidate mechanisms that could lead to the development of new therapeutic agents. His research encompasses a blend of innovative synthetic methodologies and biological evaluations, striving to bridge Award and Honor Prof. Dr. Joao Henrique Ghilardi Lago has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to the field of organic and medicinal chemistry. 🏆 His accolades highlight his exceptional research achievements, including prestigious fellowships and grants that have supported his innovative investigations in natural products chemistry and drug discovery. Dr. Lago’s work has been consistently recognized for its impact on advancing scientific knowledge and addressing critical challenges in pharmaceutical science. His dedication to excellence and pioneering research methodologies has earned him the respect of his peers and the admiration of the scientific community. These honors underscore Dr. Lago’s significant role in shaping the future of chemical research and his ongoing commitment to excellence in academia and beyond. 🌟 Research Skills Prof. Dr. Joao Henrique Ghilardi Lago is highly skilled in conducting rigorous and innovative research, showcasing a profound expertise in organic synthesis, natural products chemistry, and medicinal chemistry. 🧪 His research skills encompass the design and execution of complex synthetic pathways to access novel compounds of biological interest. Dr. Lago excels in applying state-of-the-art analytical techniques to characterize and elucidate the structures of synthesized molecules, ensuring precision and accuracy in his findings. His proficiency extends to conducting biological evaluations to assess the pharmacological potential and mechanisms of action of synthesized compounds, contributing to the advancement of drug discovery and development. Dr. Lago’s research prowess is underscored by his ability to integrate diverse scientific disciplines, fostering collaborations that enrich the scope and impact of his investigations. With a commitment to excellence and innovation, he continues to push the boundaries of chemical research, making significant contributions to the field. 🌟 Publications 📚2012 Title: The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II Journal: Current Medicinal Chemistry Citation: 375 Authors: TJ Schmidt, SA Khalid, ÁJ Romanha, TMA Alves, MW Biavatti, R Brun, … 📚2004 Title: Benzoic Acid Derivatives from Piper Species and Their Fungitoxic Activity against Cladosporium cladosporioides and C. sphaerospermum Journal: Journal of Natural Products Citation: 271 Authors: JHG Lago, CS Ramos, DCC Casanova, AA Morandim, DCB Bergamo, … 📚2015 Title: Antimicrobial activity of oleanolic and ursolic acids: an update Journal: Evidence-Based Complementary and Alternative Medicine Citation: 249 Authors: JA Jesus, JHG Lago, MD Laurenti, ES Yamamoto, LFD Passero 📚2011 Title: α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model Journal: Biochemical and Biophysical Research Communications Citation: 234 Authors: AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, … 📚2014 Title: Structure-activity association of flavonoids in lung diseases Journal: Molecules Citation: 218 Authors: JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa, MA Martins, … 📚2012 Title: The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics Journal: Molecules Citation: 175 Authors: JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, … 📚2003 Title: Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth Journal: Phytochemistry Citation: 171 Authors: AP Danelutte, JHG Lago, MCM Young, MJ Kato 📚2004 Title: Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil Journal: Journal of Chromatography A Citation: 143 Authors: S Aued-Pimentel, JHG Lago, MH Chaves, EE Kumagai 📚2003 Title: Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum Journal: Phytochemistry Citation: 138 Authors: RCC Martins, JHG Lago, S Albuquerque, MJ Kato 📚2012 Title: In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC.(Asteraceae) Journal: Experimental Parasitology Citation: 132 Authors: SS Grecco, JQ Reimão, AG Tempone, P Sartorelli, RLOR Cunha, … 📚2007 Title: Constituintes fenólicos polares de Schinus terebinthifolius Raddi (Anacardiaceae) Journal: Química Nova Citation: 117 Authors: M Ceruks, P Romoff, OA Fávero, JHG Lago 📚2015 Title: Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo Journal: Biochemical and Biophysical Research Communications Citation: 107 Authors: N Girola, CR Figueiredo, CF Farias, RA Azevedo, AK Ferreira, SF Teixeira, … 📚2013 Title: Flavonone treatment reverses airway inflammation and remodeling in an asthma murine model Journal: British Journal of Pharmacology Citation: 106 Authors: AC Toledo, CPP Sakoda, A Perini, NM Pinheiro, RM Magalhaes, … 📚2006 Title: Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae) Journal: Phytochemistry Citation: 105 Authors: ROS Kitamura, P Romoff, MCM Young, MJ Kato, JHG Lago 📚2013 Title: Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound α-Zingiberene and Derivatives Journal: Molecules Citation: 101 Authors: DD Bou, JHG Lago, CR Figueiredo, AL Matsuo, RC Guadagnin, … 📚2006 Title: Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth Journal: Phytochemistry Citation: 99 Authors: LF Yamaguchi, JHG Lago, TM Tanizaki, P Di Mascio, MJ Kato 📚2003 Title: Antifungal aromadendrane sesquiterpenoids from the leaves of Xylopia brasiliensis Journal: Journal of the Brazilian Chemical Society Citation: 91 Authors: IC Moreira, JHG Lago, MCM Young, NF Roque 📚2011 Title: Chemical and Biological Evaluation of Essential Oils from Two Species of Myrtaceae — Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel Journal: Molecules Citation: 87 Authors: JHG Lago, ED Souza, B Mariane, R Pascon, MA Vallim, RCC Martins, … 📚2012 Title: Essential oils from Schinus terebinthifolius leaves – chemical composition and in vitro cytotoxicity evaluation Journal: Pharmaceutical Biology Citation: 86 Authors: JS Santana, P Sartorelli, RC Guadagnin, AL Matsuo, CR Figueiredo, … 📚2016 Title: Evidences of herbal medicine‐derived natural products effects in inflammatory lung diseases Journal: Mediators of Inflammation Citation: 82 Authors: FPR Santana, NM Pinheiro, MIB Mernak, RF Righetti, MA Martins, … 📚2002 Title: Terpenoids from Guarea guidonia Journal: Phytochemistry Citation: 80 Authors: JHG Lago, CB Brochini, NF Roque 📚2016 Title: Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase … Journal: Phytomedicine Citation: 78 Authors: C Vizetto-Duarte, L Custódio, KN Gangadhar, JHG Lago, C Dias, … 📚2015 Title: The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programmed Cell Death and Presents Therapeutic Potential in Experimental … Journal: PLoS One Citation: 78 Authors: ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti, SP Ribeiro, … 📚2012 Title: Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo Journal: PLoS One Citation: 76 Authors: MH Massaoka, AL Matsuo, CR Figueiredo, CF Farias, N Girola, …
Kazuaki Iahihara | Chemistry and Materials Science | Best Researcher Award Nagoya University Posted on 14/06/202414/06/2024 by sciencefatherLeave a Comment on Kazuaki Iahihara | Chemistry and Materials Science | Best Researcher Award Nagoya University Prof Dr Kazuaki Iahihara | Chemistry and Materials Science | Best Researcher Award Graduate School of Engineering of Nagoya University, Japan 🎓 Prof. Dr. Kazuaki Ishihara was born on April 26, 1963, in Aichi Prefecture, Japan. He completed his Bachelor’s, Master’s, and Doctorate in Engineering at Nagoya University under the supervision of Professor Hisashi Yamamoto. 🌏 He was a visiting scholar at the University of California, Berkeley, in 1987, and a postdoctoral fellow at Harvard University under Professor E. J. Corey from 1991 to 1992. Since 2002, he has been a full professor at Nagoya University’s Department of Biotechnology. 🏅 Prof. Ishihara’s work has earned him numerous accolades, including the JSPS Prize, the IBM Science Prize, and the Chemistry Leader Award 2023. His research focuses on developing catalytic organic reactions for green chemistry, with significant contributions in designing chiral Brønsted acid–Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. 🧪 He has published 289 original papers, 139 review articles, and holds 87 patents. Additionally, Prof. Ishihara is actively involved in editorial roles for several scientific journals, including the Asian Journal of Organic Chemistry. Professional Profile: Google Scholar Education 🎓 Prof. Dr. Kazuaki Ishihara completed his entire higher education at Nagoya University in Japan. He earned his Bachelor of Engineering degree (1982-1986), followed by a Master of Engineering (1986-1988), and finally a Doctor of Engineering (1988-1991), all under the supervision of Professor Hisashi Yamamoto. 🌏 During his doctoral studies, he was a visiting scholar for three months in 1987 at the University of California, Berkeley, under Professor Clayton H. Heathcock. His doctoral thesis was titled “Studies on Stereoselective Reactions of Acetals.” Professional Experience 🏢 Prof. Dr. Kazuaki Ishihara began his professional career as a Postdoctoral Fellow at Harvard University under Professor E. J. Corey from 1991 to 1992. He then returned to Nagoya University, where he served as an Assistant Professor in the Department of Applied Chemistry (1992-1994) and later in the Department of Biotechnology (1994-1997). 🧪 He was promoted to Associate Professor at the Research Center of Waste and Emission Management (1997-2001) and subsequently in the Department of Biotechnology (2001-2002). Since 2002, he has held the position of Full Professor in the Department of Biotechnology, Graduate School of Engineering at Nagoya University. Throughout his career, Prof. Ishihara has made significant contributions to the field of green chemistry and the design of innovative catalysts. Research Interest 🔬 Prof. Dr. Kazuaki Ishihara has dedicated his research to the advancement of catalytic organic reactions and processes with a strong emphasis on green chemistry. His work spans several key areas, including the design of chiral Brønsted acid–Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. 🧪 He has also focused on developing dehydrative condensation catalysts, artificial cyclases for synthesizing optically active polycyclic terpenoids, and recoverable and reusable catalysts. 🧬 Since 2009, his research has extended to supramolecular acid–base combined catalysts. Prof. Ishihara’s innovative contributions aim to create environmentally benign synthetic methods, enhancing the sustainability and efficiency of chemical processes. Award and Honor 🏆 Prof. Dr. Kazuaki Ishihara has received numerous prestigious awards and honors throughout his illustrious career. Early in his career, he was awarded the JSPS Fellowship for Japanese Junior Scientists (1988-1991) and the Yamada Science Foundation Fellowship for Studying Abroad (1991-1992). 🥇 His groundbreaking research earned him the 10th Inoue Research Award for Young Scientists (1994) and the 45th Young Chemist Award from the Chemical Society of Japan (1996). He has also been honored with the 21st Japan IBM Science Prize (2007), the 27th Inoue Prize for Science (2011), and the Chemistry Leader Award 2023. 📜 Other notable accolades include multiple Asian Core Program Lectureship Awards, the SSOCJ Daiichi-Sankyo Award for Medicinal Organic Chemistry (2012), the Yazaki Academic Award (2013), and the CSJ Award (2017). 🌟 Prof. Ishihara’s commitment to green chemistry and innovative catalyst design has cemented his reputation as a leading figure in his field, earning him fellowships and awards from esteemed organizations worldwide. Research Skills 🧑🔬 🧬 Prof. Dr. Kazuaki Ishihara is renowned for his exceptional research skills in the field of organic chemistry, particularly in developing innovative catalytic processes. He excels in the design and synthesis of chiral Brønsted acid–Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. 🧪 His expertise extends to creating dehydrative condensation catalysts and artificial cyclases for the synthesis of optically active polycyclic terpenoids. 🧬 Prof. Ishihara is adept at designing recoverable and reusable catalysts, as well as supramolecular acid–base combined catalysts. His comprehensive approach to research, which emphasizes environmental sustainability, has led to significant advancements in green chemistry and the development of efficient, eco-friendly synthetic methods. Publications Asymmetric direct aldol reaction assisted by water and a proline‐derived tetrazole catalyst 🧑🔬 H Torii, M Nakadai, K Ishihara, S Saito, H Yamamoto 📰 Angewandte Chemie International Edition 43 (15), 1983-1986 📅 2004 🔢 674 citations 3, 4, 5-Trifluorobenzeneboronic acid as an extremely active amidation catalyst 🧑🔬 K Ishihara, S Ohara, H Yamamoto 📰 The Journal of Organic Chemistry 61 (13), 4196-4197 📅 1996 🔢 584 citations Scandium trifluoromethanesulfonate as an extremely active Lewis acid catalyst in acylation of alcohols with acid anhydrides and mixed anhydrides 🧑🔬 K Ishihara, M Kubota, H Kurihara, H Yamamoto 📰 The Journal of Organic Chemistry 61 (14), 4560-4567 📅 1996 🔢 539 citations Enantioselective Kita oxidative spirolactonization catalyzed by in situ generated chiral hypervalent iodine (III) species 🧑🔬 M Uyanik, T Yasui, K Ishihara 📰 Angewandte Chemie International Edition 12 (49), 2175-2177 📅 2010 🔢 487 citations Quaternary ammonium (hypo) iodite catalysis for enantioselective oxidative cycloetherification 🧑🔬 M Uyanik, H Okamoto, T Yasui, K Ishihara 📰 Science 328 (5984), 1376-1379 📅 2010 🔢 448 citations Enantioselective halocyclization of polyprenoids induced by nucleophilic phosphoramidites 🧑🔬 A Sakakura, A Ukai, K Ishihara 📰 Nature 445 (7130), 900-903 📅 2007 🔢 404 citations Direct condensation of carboxylic acids with alcohols catalyzed by hafnium (IV) salts 🧑🔬 K Ishihara, S Ohara, H Yamamoto 📰 Science 290 (5494), 1140-1142 📅 2000 🔢 395 citations 2-Iodoxybenzenesulfonic acid as an extremely active catalyst for the selective oxidation of alcohols to aldehydes, ketones, carboxylic acids, and enones with oxone 🧑🔬 M Uyanik, M Akakura, K Ishihara 📰 Journal of the American Chemical Society 131 (1), 251-262 📅 2009 🔢 370 citations In situ generated (hypo) iodite catalysts for the direct α‐oxyacylation of carbonyl compounds with carboxylic acids 🧑🔬 M Uyanik, D Suzuki, T Yasui, K Ishihara 📰 Angewandte Chemie International Edition 23 (50), 5331-5334 📅 2011 🔢 369 citations Highly enantioselective catalytic Diels-Alder addition promoted by a chiral bis (oxazoline)-magnesium complex 🧑🔬 EJ Corey, K Ishihara 📰 Tetrahedron Letters 33 (45), 6807-6810 📅 1992 🔢 368 citations Scandium trifluoromethanesulfonate as an extremely active acylation catalyst 🧑🔬 K Ishihara, M Kubota, H Kurihara, H Yamamoto 📰 Journal of the American Chemical Society 117 (15), 4413-4414 📅 1995 🔢 329 citations Hypervalent iodine-mediated oxidation of alcohols 🧑🔬 M Uyanik, K Ishihara 📰 Chemical Communications, 2086-2099 📅 2009 🔢 307 citations A new chiral BLA promoter for asymmetric aza Diels-Alder and Aldol-type reactions of imines 🧑🔬 K Ishihara, M Miyata, K Hattori, T Tada, H Yamamoto 📰 Journal of the American Chemical Society 116 (23), 10520-10524 📅 1994 🔢 283 citations Widely useful DMAP-catalyzed esterification under auxiliary base-and solvent-free conditions 🧑🔬 A Sakakura, K Kawajiri, T Ohkubo, Y Kosugi, K Ishihara 📰 Journal of the American Chemical Society 129 (47), 14775-14779 📅 2007 🔢 281 citations Catalysis with in situ‐generated (hypo) iodite ions for oxidative coupling reactions 🧑🔬 M Uyanik, K Ishihara 📰 ChemCatChem 4 (2), 177-185 📅 2012 🔢 270 citations