Kazuaki Iahihara | Chemistry and Materials Science | Best Researcher Award Nagoya University

Prof Dr Kazuaki Iahihara | Chemistry and Materials Science | Best Researcher Award

ย Graduate School of Engineering of Nagoya University, Japan

๐ŸŽ“ Prof. Dr. Kazuaki Ishihara was born on April 26, 1963, in Aichi Prefecture, Japan. He completed his Bachelorโ€™s, Masterโ€™s, and Doctorate in Engineering at Nagoya University under the supervision of Professor Hisashi Yamamoto. ๐ŸŒ He was a visiting scholar at the University of California, Berkeley, in 1987, and a postdoctoral fellow at Harvard University under Professor E. J. Corey from 1991 to 1992. Since 2002, he has been a full professor at Nagoya Universityโ€™s Department of Biotechnology. ๐Ÿ… Prof. Ishiharaโ€™s work has earned him numerous accolades, including the JSPS Prize, the IBM Science Prize, and the Chemistry Leader Award 2023. His research focuses on developing catalytic organic reactions for green chemistry, with significant contributions in designing chiral Brรธnsted acidโ€“Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. ๐Ÿงช He has published 289 original papers, 139 review articles, and holds 87 patents. Additionally, Prof. Ishihara is actively involved in editorial roles for several scientific journals, including the Asian Journal of Organic Chemistry.

Professional Profile:

Education

๐ŸŽ“ Prof. Dr. Kazuaki Ishihara completed his entire higher education at Nagoya University in Japan. He earned his Bachelor of Engineering degree (1982-1986), followed by a Master of Engineering (1986-1988), and finally a Doctor of Engineering (1988-1991), all under the supervision of Professor Hisashi Yamamoto. ๐ŸŒ During his doctoral studies, he was a visiting scholar for three months in 1987 at the University of California, Berkeley, under Professor Clayton H. Heathcock. His doctoral thesis was titled “Studies on Stereoselective Reactions of Acetals.”

 

Professional Experience

 

๐Ÿข Prof. Dr. Kazuaki Ishihara began his professional career as a Postdoctoral Fellow at Harvard University under Professor E. J. Corey from 1991 to 1992. He then returned to Nagoya University, where he served as an Assistant Professor in the Department of Applied Chemistry (1992-1994) and later in the Department of Biotechnology (1994-1997). ๐Ÿงช He was promoted to Associate Professor at the Research Center of Waste and Emission Management (1997-2001) and subsequently in the Department of Biotechnology (2001-2002). Since 2002, he has held the position of Full Professor in the Department of Biotechnology, Graduate School of Engineering at Nagoya University. Throughout his career, Prof. Ishihara has made significant contributions to the field of green chemistry and the design of innovative catalysts.

Research Interest

๐Ÿ”ฌ Prof. Dr. Kazuaki Ishihara has dedicated his research to the advancement of catalytic organic reactions and processes with a strong emphasis on green chemistry. His work spans several key areas, including the design of chiral Brรธnsted acidโ€“Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. ๐Ÿงช He has also focused on developing dehydrative condensation catalysts, artificial cyclases for synthesizing optically active polycyclic terpenoids, and recoverable and reusable catalysts. ๐Ÿงฌ Since 2009, his research has extended to supramolecular acidโ€“base combined catalysts. Prof. Ishihara’s innovative contributions aim to create environmentally benign synthetic methods, enhancing the sustainability and efficiency of chemical processes.

Award and Honor

๐Ÿ† Prof. Dr. Kazuaki Ishihara has received numerous prestigious awards and honors throughout his illustrious career. Early in his career, he was awarded the JSPS Fellowship for Japanese Junior Scientists (1988-1991) and the Yamada Science Foundation Fellowship for Studying Abroad (1991-1992). ๐Ÿฅ‡ His groundbreaking research earned him the 10th Inoue Research Award for Young Scientists (1994) and the 45th Young Chemist Award from the Chemical Society of Japan (1996). He has also been honored with the 21st Japan IBM Science Prize (2007), the 27th Inoue Prize for Science (2011), and the Chemistry Leader Award 2023. ๐Ÿ“œ Other notable accolades include multiple Asian Core Program Lectureship Awards, the SSOCJ Daiichi-Sankyo Award for Medicinal Organic Chemistry (2012), the Yazaki Academic Award (2013), and the CSJ Award (2017). ๐ŸŒŸ Prof. Ishiharaโ€™s commitment to green chemistry and innovative catalyst design has cemented his reputation as a leading figure in his field, earning him fellowships and awards from esteemed organizations worldwide.

 

Research Skills

 

๐Ÿง‘โ€๐Ÿ”ฌ ๐Ÿงฌ Prof. Dr. Kazuaki Ishihara is renowned for his exceptional research skills in the field of organic chemistry, particularly in developing innovative catalytic processes. He excels in the design and synthesis of chiral Brรธnsted acidโ€“Lewis acid combined catalysts, superacids, and hypervalent iodine catalysts. ๐Ÿงช His expertise extends to creating dehydrative condensation catalysts and artificial cyclases for the synthesis of optically active polycyclic terpenoids. ๐Ÿงฌ Prof. Ishihara is adept at designing recoverable and reusable catalysts, as well as supramolecular acidโ€“base combined catalysts. His comprehensive approach to research, which emphasizes environmental sustainability, has led to significant advancements in green chemistry and the development of efficient, eco-friendly synthetic methods.

Publications

  • Asymmetric direct aldol reaction assisted by water and a prolineโ€derived tetrazole catalyst
    ๐Ÿง‘โ€๐Ÿ”ฌ H Torii, M Nakadai, K Ishihara, S Saito, H Yamamoto
    ๐Ÿ“ฐ Angewandte Chemie International Edition 43 (15), 1983-1986
    ๐Ÿ“… 2004
    ๐Ÿ”ข 674 citations
  • 3, 4, 5-Trifluorobenzeneboronic acid as an extremely active amidation catalyst
    ๐Ÿง‘โ€๐Ÿ”ฌ K Ishihara, S Ohara, H Yamamoto
    ๐Ÿ“ฐ The Journal of Organic Chemistry 61 (13), 4196-4197
    ๐Ÿ“… 1996
    ๐Ÿ”ข 584 citations
  • Scandium trifluoromethanesulfonate as an extremely active Lewis acid catalyst in acylation of alcohols with acid anhydrides and mixed anhydrides
    ๐Ÿง‘โ€๐Ÿ”ฌ K Ishihara, M Kubota, H Kurihara, H Yamamoto
    ๐Ÿ“ฐ The Journal of Organic Chemistry 61 (14), 4560-4567
    ๐Ÿ“… 1996
    ๐Ÿ”ข 539 citations
  • Enantioselective Kita oxidative spirolactonization catalyzed by in situ generated chiral hypervalent iodine (III) species
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, T Yasui, K Ishihara
    ๐Ÿ“ฐ Angewandte Chemie International Edition 12 (49), 2175-2177
    ๐Ÿ“… 2010
    ๐Ÿ”ข 487 citations
  • Quaternary ammonium (hypo) iodite catalysis for enantioselective oxidative cycloetherification
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, H Okamoto, T Yasui, K Ishihara
    ๐Ÿ“ฐ Science 328 (5984), 1376-1379
    ๐Ÿ“… 2010
    ๐Ÿ”ข 448 citations
  • Enantioselective halocyclization of polyprenoids induced by nucleophilic phosphoramidites
    ๐Ÿง‘โ€๐Ÿ”ฌ A Sakakura, A Ukai, K Ishihara
    ๐Ÿ“ฐ Nature 445 (7130), 900-903
    ๐Ÿ“… 2007
    ๐Ÿ”ข 404 citations
  • Direct condensation of carboxylic acids with alcohols catalyzed by hafnium (IV) salts
    ๐Ÿง‘โ€๐Ÿ”ฌ K Ishihara, S Ohara, H Yamamoto
    ๐Ÿ“ฐ Science 290 (5494), 1140-1142
    ๐Ÿ“… 2000
    ๐Ÿ”ข 395 citations
  • 2-Iodoxybenzenesulfonic acid as an extremely active catalyst for the selective oxidation of alcohols to aldehydes, ketones, carboxylic acids, and enones with oxone
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, M Akakura, K Ishihara
    ๐Ÿ“ฐ Journal of the American Chemical Society 131 (1), 251-262
    ๐Ÿ“… 2009
    ๐Ÿ”ข 370 citations
  • In situ generated (hypo) iodite catalysts for the direct ฮฑโ€oxyacylation of carbonyl compounds with carboxylic acids
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, D Suzuki, T Yasui, K Ishihara
    ๐Ÿ“ฐ Angewandte Chemie International Edition 23 (50), 5331-5334
    ๐Ÿ“… 2011
    ๐Ÿ”ข 369 citations
  • Highly enantioselective catalytic Diels-Alder addition promoted by a chiral bis (oxazoline)-magnesium complex
    ๐Ÿง‘โ€๐Ÿ”ฌ EJ Corey, K Ishihara
    ๐Ÿ“ฐ Tetrahedron Letters 33 (45), 6807-6810
    ๐Ÿ“… 1992
    ๐Ÿ”ข 368 citations
  • Scandium trifluoromethanesulfonate as an extremely active acylation catalyst
    ๐Ÿง‘โ€๐Ÿ”ฌ K Ishihara, M Kubota, H Kurihara, H Yamamoto
    ๐Ÿ“ฐ Journal of the American Chemical Society 117 (15), 4413-4414
    ๐Ÿ“… 1995
    ๐Ÿ”ข 329 citations
  • Hypervalent iodine-mediated oxidation of alcohols
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, K Ishihara
    ๐Ÿ“ฐ Chemical Communications, 2086-2099
    ๐Ÿ“… 2009
    ๐Ÿ”ข 307 citations
  • A new chiral BLA promoter for asymmetric aza Diels-Alder and Aldol-type reactions of imines
    ๐Ÿง‘โ€๐Ÿ”ฌ K Ishihara, M Miyata, K Hattori, T Tada, H Yamamoto
    ๐Ÿ“ฐ Journal of the American Chemical Society 116 (23), 10520-10524
    ๐Ÿ“… 1994
    ๐Ÿ”ข 283 citations
  • Widely useful DMAP-catalyzed esterification under auxiliary base-and solvent-free conditions
    ๐Ÿง‘โ€๐Ÿ”ฌ A Sakakura, K Kawajiri, T Ohkubo, Y Kosugi, K Ishihara
    ๐Ÿ“ฐ Journal of the American Chemical Society 129 (47), 14775-14779
    ๐Ÿ“… 2007
    ๐Ÿ”ข 281 citations
  • Catalysis with in situโ€generated (hypo) iodite ions for oxidative coupling reactions
    ๐Ÿง‘โ€๐Ÿ”ฌ M Uyanik, K Ishihara
    ๐Ÿ“ฐ ChemCatChem 4 (2), 177-185
    ๐Ÿ“… 2012
    ๐Ÿ”ข 270 citations