Ajmer Singh Grewal | Drug Discovery | Best Researcher Award

Prof. Ajmer Singh Grewal | Drug Discovery | Best Researcher Award

 Professor at Guru Gobind Singh College of Pharmacy, India

Amelia Sweet is a dedicated graduate student pursuing a Ph.D. in Computational Chemistry at the University of Iowa. With a strong background in both theoretical and applied chemistry, Amelia focuses on the study of molecular interactions and surface phenomena. Her research involves advanced computational techniques and has resulted in several notable publications and presentations. Amelia’s professional journey reflects a commitment to both research and education in the field of chemistry.

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Amelia Sweet has demonstrated notable contributions to the field of computational chemistry, evidenced by her publications and presentations. Her work on DFT studies and adsorption phenomena has garnered attention in scientific communities, as shown by her published paper in Surface Science and multiple presentations at significant chemistry conferences.

  • Citations: 1,703 across 1,451 documents
  • Documents: 102
  • h-index: 19

Education

Amelia completed her Bachelor of Arts in Chemistry from Saint Mary’s University of Minnesota in May 2020, where she received the American Chemical Society Award for her thesis work on tungsten-based polyoxometalates. She is currently pursuing a Ph.D. in Chemistry at the University of Iowa, under the co-advisement of Dr. Sara Mason and Dr. Scott Shaw. Her doctoral research focuses on computational studies of molecular adsorption and interactions.

Research Focus

Amelia’s research primarily revolves around the use of Density Functional Theory (DFT) to study molecular interactions with metal surfaces. Her work involves conducting DFT calculations using VASP and performing adsorption studies of organic molecules, specifically nitrobenzene, on metal surfaces like Ag(111). Her research aims to deepen the understanding of surface chemistry and adsorption phenomena.

Professional Journey

Amelia’s professional journey includes roles as a Research Assistant and Teaching Assistant at the University of Iowa. As a Research Assistant, she has been engaged in conducting periodic DFT calculations and studying adsorption processes. Her experience as a Teaching Assistant involved instructing undergraduate students in introductory chemistry and analytical measurements laboratories. Additionally, Amelia participated in a Research Experience for Undergraduates (REU) program at Coe College, where she developed scintillating glass for high-energy applications.

Honors & Awards

Amelia was honored with the American Chemical Society Award during her undergraduate studies for her exceptional thesis on tungsten-based polyoxometalates. This recognition highlights her academic excellence and potential in the field of chemistry.

Publications Noted & Contributions

Amelia has contributed to several key publications and presentations in her field. Notably, she has published an article on the interaction of nitrobenzene with the Ag(111) surface in Surface Science. Her research has also been presented at various conferences, including the Midwest and National Meetings of the American Chemical Society, showcasing her work on molecular adsorption and DFT studies.

Books and Book Chapters

Title: Naturally Occurring Chemicals for the Treatment and Management of Diabetes Mellitus and Related Disorders

  • Year: 2024
  • DOI: 10.52305/WBBQ6236
  • Contributors: Ajmer Singh Grewal, Geeta Deswal, Ashwani Kumar Dhingra, Priyanka Kriplani, Bhawna Chopra, Shikha Baghel Chauhan

Journal Articles

Title: Aaptamine: A Versatile Marine Alkaloid for Antioxidant, Antibacterial, and Anticancer Therapeutics

  • Journal: Chemistry
  • Date: August 3, 2024
  • DOI: 10.3390/chemistry6040040
  • Contributors: Navin Kumar Tailor, Geeta Deswal, Ajmer Singh Grewal

Title: Benefits of Medicinal Plants in Boosting Immunity against Viral Infections Including COVID-19

Title: Novel Cinnamic Acid Derivatives as Potential Anticancer Agents: Synthesis, In Vitro Cytotoxicity and Molecular Docking Studies

  • Journal: Biointerface Research in Applied Chemistry
  • Year: 2023
  • DOI: 10.33263/BRIAC132.150
  • EID: 2-s2.0-85127986213
  • Contributors: Kaur, P., Grewal, A.S., Pandita, D., Lather, V.

Title: Role of Medicinal Plants in the Management of Inflammatory Disorders: An Overview

  • Journal: Recent Advances in Inflammation & Allergy Drug Discovery
  • Year: 2023
  • DOI: 10.2174/2772270817666230227140659
  • WOSUID: WOS:001042798300004
  • Contributors: Garg, Madhukar; Sharma, Abhinav; Bansal, Shivam; Grover, Rupanshi; Sharma, Tanya; Kumari, Sapna; Goyal, Anju; Bhatia, Shiveena; Vaid, Lavish; Deswal, Geeta et al.

Research Timeline

Amelia’s research timeline includes her initial work in the REU program in 2019, followed by her continued research and doctoral studies starting in 2020. Her current research involves ongoing studies of adsorption phenomena and DFT calculations. Key milestones include her presentations and publications from 2022 to 2024, reflecting the progression and impact of her research.

Collaborations and Projects

Amelia’s research is collaborative, involving work with Dr. Sara Mason and Dr. Scott Shaw at the University of Iowa. Her projects include the study of molecular adsorption using computational methods and the development of educational materials for teaching collaborative science. Her collaborative efforts extend to presenting and publishing research findings in partnership with other chemists and educators.

Strengths of the Best Researcher Award

  1. Significant Research Contributions: Prof. Ajmer Singh Grewal’s extensive publication record demonstrates a deep and impactful contribution to drug discovery and medicinal chemistry. His research on naturally occurring chemicals and medicinal plants is highly relevant and influential.
  2. Diverse Research Topics: The breadth of his work, ranging from diabetes management to anticancer agents and antioxidant therapeutics, highlights his versatility and comprehensive approach to medicinal chemistry.
  3. High Citation Metrics: With 1,703 citations across 1,451 documents and an h-index of 19, Prof. Grewal’s work is well-recognized and respected in the scientific community, indicating significant influence and impact.
  4. Collaboration with Renowned Researchers: His collaborations with prominent researchers, such as Geeta Deswal and Ashwani Kumar Dhingra, enhance the quality and reach of his research, contributing to its high visibility and credibility.
  5. Recognition and Awards: The Best Researcher Award is a testament to Prof. Grewal’s contributions to the field. It acknowledges his excellence in research and his role in advancing drug discovery.

Areas for Improvement

  1. Research Focus Narrowing: While the diversity of research topics is a strength, narrowing the focus to a few key areas could lead to more in-depth studies and potentially more groundbreaking discoveries.
  2. Public Engagement: Increasing public engagement through popular science articles or community outreach can help translate his research into broader societal benefits and enhance public understanding of his work.
  3. Interdisciplinary Research: Expanding into interdisciplinary research areas, such as combining drug discovery with biotechnology or artificial intelligence, could provide new insights and opportunities for innovation.
  4. Collaborative Efforts: Although collaborations are strong, fostering new partnerships with institutions or researchers in different regions or fields could provide fresh perspectives and broaden the scope of research.
  5. Funding and Resources: Securing additional funding and resources could enhance research capabilities, allowing for more extensive studies and the development of new technologies or methodologies.

Conclusion

Prof. Ajmer Singh Grewal’s recognition with the Best Researcher Award reflects his outstanding contributions to the field of drug discovery and medicinal chemistry. His research spans a wide range of topics and has significantly impacted the scientific community, as evidenced by his high citation metrics and collaborative efforts. While there are areas for improvement, such as narrowing research focus and enhancing public engagement, Prof. Grewal’s accomplishments highlight his leadership and influence in advancing medicinal chemistry. His future work, potentially incorporating interdisciplinary approaches and expanded collaborations, promises to further elevate his impact on the field.

Joao Lago | Pharmacology | Best Researcher Award

Prof Dr. Joao Lago | Pharmacology | Best Researcher Award 

Professor at Federal University of ABC, Brazil

Prof. Dr. Joao Henrique Ghilardi Lago is a distinguished researcher in Chemistry, specializing in the Chemistry of Natural Products. With extensive academic credentials including a Ph.D. from the University of São Paulo and a background in both chemical education and research, he has made significant contributions to the field. His current position at the Federal University of ABC reflects his commitment to teaching and research in biosystems and organic chemistry. 🌿🔬 Dr. Lago’s work is marked by his leadership in various research projects focusing on the characterization and potential applications of specialized metabolites from Brazilian flora, particularly in combating neglected tropical diseases. His role as a grantee and reviewer for multiple scientific funding agencies underscores his influence and expertise in the scientific community, contributing to the advancement of bioorganic chemistry and pharmaceutical research in Brazil and beyond. 🌍

Professional Profile:

Education

Prof. Dr. Joao Henrique Ghilardi Lago pursued a rigorous academic journey culminating in his esteemed position in the scientific community. He earned his Bachelor’s degree in Chemistry from the Federal University of Mato Grosso do Sul (UFMS), Brazil, before advancing to achieve a Master’s and Ph.D. in Chemistry from the University of São Paulo (USP), one of Brazil’s leading institutions. 🎓 His doctoral research focused on natural products chemistry, a field he has since dedicated himself to with passion and expertise. Througho ut his educational path, Dr. Lago has demonstrated a commitment to excellence in scientific inquiry and a deep understanding of organic chemistry principles. His academic background has equipped him with the skills and knowledge to lead impactful research initiatives, particularly in the chemistry of natural products and their potential applications in medicine and pharmacology. 🌿🔬

Professional Experience

Prof. Dr. Joao Henrique Ghilardi Lago boasts a rich professional experience marked by significant contributions to the fields of chemistry and academia. He has held key positions such as a researcher and professor at the Federal University of Mato Grosso do Sul (UFMS), Brazil, where he has actively engaged in teaching and mentoring students while conducting groundbreaking research. 🌟 Dr. Lago’s research interests encompass natural products chemistry, medicinal chemistry, and synthetic organic chemistry, areas in which he has published numerous influential papers in prestigious scientific journals. His professional journey also includes collaborations with national and international research groups, fostering interdisciplinary approaches to tackle complex scientific challenges. As a recognized expert in his field, Dr. Lago continues to inspire and educate future generations of scientists through his dedicated work and leadership in academia. 🔍🔬

Research Interest

Prof. Dr. Joao Henrique Ghilardi Lago’s research interests are centered around the fascinating realms of natural products chemistry, medicinal chemistry, and synthetic organic chemistry. 🌿 His work delves into the exploration and synthesis of bioactive compounds derived from natural sources, aiming to uncover their potential applications in medicine and related fields. Dr. Lago is particularly intrigued by the molecular structures of natural products and their intricate biological activities, seeking to elucidate mechanisms that could lead to the development of new therapeutic agents. His research encompasses a blend of innovative synthetic methodologies and biological evaluations, striving to bridge

Award and Honor

Prof. Dr. Joao Henrique Ghilardi Lago has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to the field of organic and medicinal chemistry. 🏆 His accolades highlight his exceptional research achievements, including prestigious fellowships and grants that have supported his innovative investigations in natural products chemistry and drug discovery. Dr. Lago’s work has been consistently recognized for its impact on advancing scientific knowledge and addressing critical challenges in pharmaceutical science. His dedication to excellence and pioneering research methodologies has earned him the respect of his peers and the admiration of the scientific community. These honors underscore Dr. Lago’s significant role in shaping the future of chemical research and his ongoing commitment to excellence in academia and beyond. 🌟

Research Skills

Prof. Dr. Joao Henrique Ghilardi Lago is highly skilled in conducting rigorous and innovative research, showcasing a profound expertise in organic synthesis, natural products chemistry, and medicinal chemistry. 🧪 His research skills encompass the design and execution of complex synthetic pathways to access novel compounds of biological interest. Dr. Lago excels in applying state-of-the-art analytical techniques to characterize and elucidate the structures of synthesized molecules, ensuring precision and accuracy in his findings. His proficiency extends to conducting biological evaluations to assess the pharmacological potential and mechanisms of action of synthesized compounds, contributing to the advancement of drug discovery and development. Dr. Lago’s research prowess is underscored by his ability to integrate diverse scientific disciplines, fostering collaborations that enrich the scope and impact of his investigations. With a commitment to excellence and innovation, he continues to push the boundaries of chemical research, making significant contributions to the field. 🌟

Publications

📚2012

  • Title: The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
  • Journal: Current Medicinal Chemistry
  • Citation: 375
  • Authors: TJ Schmidt, SA Khalid, ÁJ Romanha, TMA Alves, MW Biavatti, R Brun, …

📚2004

  • Title: Benzoic Acid Derivatives from Piper Species and Their Fungitoxic Activity against Cladosporium cladosporioides and C. sphaerospermum
  • Journal: Journal of Natural Products
  • Citation: 271
  • Authors: JHG Lago, CS Ramos, DCC Casanova, AA Morandim, DCB Bergamo, …

📚2015

  • Title: Antimicrobial activity of oleanolic and ursolic acids: an update
  • Journal: Evidence-Based Complementary and Alternative Medicine
  • Citation: 249
  • Authors: JA Jesus, JHG Lago, MD Laurenti, ES Yamamoto, LFD Passero

📚2011

  • Title: α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 234
  • Authors: AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, …

📚2014

  • Title: Structure-activity association of flavonoids in lung diseases
  • Journal: Molecules
  • Citation: 218
  • Authors: JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa, MA Martins, …

📚2012

  • Title: The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics
  • Journal: Molecules
  • Citation: 175
  • Authors: JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, …

📚2003

  • Title: Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 171
  • Authors: AP Danelutte, JHG Lago, MCM Young, MJ Kato

📚2004

  • Title: Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil
  • Journal: Journal of Chromatography A
  • Citation: 143
  • Authors: S Aued-Pimentel, JHG Lago, MH Chaves, EE Kumagai

📚2003

  • Title: Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum
  • Journal: Phytochemistry
  • Citation: 138
  • Authors: RCC Martins, JHG Lago, S Albuquerque, MJ Kato

📚2012

  • Title: In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC.(Asteraceae)
  • Journal: Experimental Parasitology
  • Citation: 132
  • Authors: SS Grecco, JQ Reimão, AG Tempone, P Sartorelli, RLOR Cunha, …

📚2007

  • Title: Constituintes fenólicos polares de Schinus terebinthifolius Raddi (Anacardiaceae)
  • Journal: Química Nova
  • Citation: 117
  • Authors: M Ceruks, P Romoff, OA Fávero, JHG Lago

📚2015

  • Title: Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo
  • Journal: Biochemical and Biophysical Research Communications
  • Citation: 107
  • Authors: N Girola, CR Figueiredo, CF Farias, RA Azevedo, AK Ferreira, SF Teixeira, …

📚2013

  • Title: Flavonone treatment reverses airway inflammation and remodeling in an asthma murine model
  • Journal: British Journal of Pharmacology
  • Citation: 106
  • Authors: AC Toledo, CPP Sakoda, A Perini, NM Pinheiro, RM Magalhaes, …

📚2006

  • Title: Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae)
  • Journal: Phytochemistry
  • Citation: 105
  • Authors: ROS Kitamura, P Romoff, MCM Young, MJ Kato, JHG Lago

📚2013

  • Title: Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound α-Zingiberene and Derivatives
  • Journal: Molecules
  • Citation: 101
  • Authors: DD Bou, JHG Lago, CR Figueiredo, AL Matsuo, RC Guadagnin, …

📚2006

  • Title: Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth
  • Journal: Phytochemistry
  • Citation: 99
  • Authors: LF Yamaguchi, JHG Lago, TM Tanizaki, P Di Mascio, MJ Kato

📚2003

  • Title: Antifungal aromadendrane sesquiterpenoids from the leaves of Xylopia brasiliensis
  • Journal: Journal of the Brazilian Chemical Society
  • Citation: 91
  • Authors: IC Moreira, JHG Lago, MCM Young, NF Roque

📚2011

  • Title: Chemical and Biological Evaluation of Essential Oils from Two Species of Myrtaceae — Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel
  • Journal: Molecules
  • Citation: 87
  • Authors: JHG Lago, ED Souza, B Mariane, R Pascon, MA Vallim, RCC Martins, …

📚2012

  • Title: Essential oils from Schinus terebinthifolius leaves – chemical composition and in vitro cytotoxicity evaluation
  • Journal: Pharmaceutical Biology
  • Citation: 86
  • Authors: JS Santana, P Sartorelli, RC Guadagnin, AL Matsuo, CR Figueiredo, …

📚2016

  • Title: Evidences of herbal medicine‐derived natural products effects in inflammatory lung diseases
  • Journal: Mediators of Inflammation
  • Citation: 82
  • Authors: FPR Santana, NM Pinheiro, MIB Mernak, RF Righetti, MA Martins, …

📚2002

  • Title: Terpenoids from Guarea guidonia
  • Journal: Phytochemistry
  • Citation: 80
  • Authors: JHG Lago, CB Brochini, NF Roque

📚2016

  • Title: Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase …
  • Journal: Phytomedicine
  • Citation: 78
  • Authors: C Vizetto-Duarte, L Custódio, KN Gangadhar, JHG Lago, C Dias, …

📚2015

  • Title: The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programmed Cell Death and Presents Therapeutic Potential in Experimental …
  • Journal: PLoS One
  • Citation: 78
  • Authors: ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti, SP Ribeiro, …

📚2012

  • Title: Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo
  • Journal: PLoS One
  • Citation: 76
  • Authors: MH Massaoka, AL Matsuo, CR Figueiredo, CF Farias, N Girola, …