Assist. Prof. Dr. Changtong YANG | Medicinal Chemistry | Best Researcher Award

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Assist. Prof. Dr. Changtong YANG | Medicinal Chemistry | Best Researcher Award

Assist. Prof. Dr. Changtong YANG , Medicinal Chemistry,  Radiochemist/Chemist at Singapore General Hospital, Singapore

Dr. Chang-Tong Yang is a renowned radiochemist based in Singapore, specializing in radiopharmaceuticals and molecular imaging. He currently serves as an Assistant Professor in the Radiological Science Academic Clinical Programme at Duke-NUS Medical School and as a Radiochemist at Singapore General Hospital. With over two decades of experience, Dr. Yang has made significant contributions to the development of nuclear imaging probes and radiolabeled therapeutics. His research career spans prestigious institutions, including Nanyang Technological University and A*STAR. Dr. Yang is internationally recognized for advancing nanomaterial probes and novel radiolabeling strategies. He has authored impactful publications in top-tier journals, reflecting his innovation in theranostics, radiochemistry, and nanomedicine. With a strong background in academic and clinical research, Dr. Yang continues to shape the future of molecular imaging for personalized medicine. His global education and interdisciplinary expertise make him a leading figure in translational radiochemistry research.

Professional Profile : 

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Summary of Suitability for Award:

Dr. Chang-Tong Yang exemplifies the qualities of a “Best Researcher Award” recipient. His innovative contributions to radiochemistry and molecular imaging, combined with a strong publication record, interdisciplinary leadership, and global training, establish him as a trailblazer in translational medical research. His work is not only scientifically rigorous but also clinically impactful, directly advancing the field of nuclear medicine. Therefore, he is highly recommended for recognition as a top-tier researcher deserving of this award.

🎓Education:

Dr. Chang-Tong Yang received his Ph.D. in Chemistry from the National University of Singapore (1998–2002), where he laid the foundation for his career in radiochemistry. He further enhanced his expertise with postdoctoral fellowships at three prestigious U.S. institutions: University of Iowa (2003–2005), University of Michigan (2005–2006), and Purdue University (2006–2007), focusing on chemistry and health sciences. These formative years provided Dr. Yang with a multidisciplinary perspective in synthetic chemistry, radiopharmaceutical development, and imaging sciences. His international training exposed him to cutting-edge methodologies and collaborative projects across biomedical research, which he has since translated into innovative imaging solutions. The combination of rigorous education and hands-on research across these top institutions shaped his ability to bridge fundamental science with clinical applications, particularly in nuclear medicine and molecular imaging.

🏢Work Experience:

Dr. Chang-Tong Yang brings extensive professional experience across both academic and clinical research settings. He is currently an Assistant Professor at Duke-NUS Medical School (2020–present) under the Radiological Science ACP, focusing on radiopharmaceutical sciences. Concurrently, he serves as a Radiochemist at Singapore General Hospital (2018–present) in the Department of Nuclear Medicine & Molecular Imaging, where he translates research into clinical practice. Prior to that, he worked as a Senior Scientist at Nanyang Technological University (2014–2018), contributing to molecular imaging initiatives within the Lee Kong Chian School of Medicine. He also held a Senior Scientist role at A*STAR’s Singapore Bio-Imaging Consortium (2007–2014), leading various radiochemistry research programs. Across these roles, Dr. Yang has developed and validated imaging agents, optimized radiolabeling techniques, and led translational studies that impact diagnostic imaging and therapeutic strategies. His multidisciplinary engagements underscore his pivotal role in bridging chemistry and medicine.

🏅Awards: 

While specific awards are not listed in the available data, Dr. Chang-Tong Yang’s extensive contributions to radiopharmaceuticals and molecular imaging reflect a highly respected and impactful career. His appointments at top institutions such as Duke-NUS, A*STAR, and Singapore General Hospital indicate peer recognition and institutional trust. His publications in reputed journals such as Molecules, Nanomaterials, and Drug Discovery Today highlight his standing in the scientific community. His ongoing leadership roles and collaboration with clinicians further underscore professional acknowledgment of his expertise. Dr. Yang’s selection for multiple postdoctoral positions at prestigious U.S. institutions—University of Iowa, University of Michigan, and Purdue University—suggests early recognition of his academic promise. His interdisciplinary contributions to nuclear medicine, nanotechnology, and molecular imaging may have earned him internal institutional awards, research grants, and invitations to present at scientific forums, which commonly accompany such roles.

🔬Research Focus:

Dr. Chang-Tong Yang’s research is centered on radiopharmaceutical science, with a strong emphasis on the development of molecular imaging probes and radiolabeled nanomaterials for diagnostic and therapeutic applications. His expertise lies in designing novel radioisotope-labeled compounds for use in nuclear medicine imaging techniques such as PET and SPECT, targeting cancer and other pathological conditions. He is particularly interested in enhancing the in vivo behavior of nanomaterial-based agents, improving tumor targeting, retention, and safety. Dr. Yang also explores the biocompatibility and stability of these probes, including how formulation and labeling protocols influence their function. His translational work bridges laboratory innovations with clinical imaging requirements, enabling personalized diagnostics and theranostic approaches. Furthermore, he investigates radiochemical compatibility in clinical settings, such as the mixing of imaging agents with contrast media, which supports safe and effective imaging protocols. His work integrates chemistry, imaging, and clinical practice seamlessly.

Publication Top Notes:

1. pH-Induced In Situ Aggregation of Cu₂₋ₓSe-POED with Extended Tumor Retention for Enhanced Chemodynamic/Photothermal Therapy

2. Standard Radio-Iodine Labeling Protocols Impaired the Functional Integrity of Mesenchymal Stem/Stromal Cell Exosomes

3. Radiolabeled Liposomes for Nuclear Imaging Probes

4. Radiochemical Feasibility of Mixing of 99mTc-MAA and 90Y-Microspheres with Omnipaque Contrast

5. Nanomaterial Probes for Nuclear Imaging

6. Positron Emission Tomographic Imaging in Drug Discovery

7. An In Vivo Study of a Rat Fluid-Percussion-Induced Traumatic Brain Injury Model with [11C]PBR28 and [18F]flumazenil PET Imaging

8. Gadolinium-Based Bimodal Probes to Enhance T1-Weighted Magnetic Resonance/Optical Imaging

9. Activatable Cell-Penetrating Peptide Conjugated Polymeric Nanoparticles with Gd-Chelation and Aggregation-Induced Emission for Bimodal MR and Fluorescence Imaging of Tumors

10. Dealing with PET Radiometabolites

11. PET-MR and SPECT-MR Multimodality Probes

 

Prof. Dr. Zhou Xu | Analytical Chemistry | Best Researcher Award

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Prof. Dr. Zhou Xu | Analytical Chemistry | Best Researcher Award

Prof. Dr. Zhou Xu , Analytical Chemistry , Assistant Dean at Changsha University of Science & Technology, China

Dr. Zhou Xu is a distinguished Professor and Assistant Dean at the School of Food Science and Bioengineering, Changsha University of Science and Technology. He earned his Ph.D. in Physical Chemistry from Jiangnan University Specializing in food safety, bio sensing, and nanomaterials, Dr. Xu has led numerous national research projects focused on food quality monitoring and rapid detection technologies. With a proven record of innovative research, he has published extensively in top-tier journals like ACS Sensors, Analytical Chemistry, and Chemical Engineering Journal. His pioneering work in biosensors, nanozymes, and magnetic relaxation sensors has earned him multiple research grants and provincial awards. Dr. Xu is recognized for integrating interdisciplinary approaches involving chemistry, biology, and materials science to address critical food safety challenges. His leadership in scientific research and education continues to influence advancements in food science, public health, and nanotechnology applications.

Professional Profile : 

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Summary of Suitability for Award:

Prof. Zhou Xu is highly suitable for nomination for the “Best Researcher Award.” He holds a Ph.D. in Physical Chemistry (2013) from Jiangnan University and currently serves as a Professor and Assistant Dean at the School of Food Science and Bioengineering, Changsha University of Science and Technology. His academic trajectory—from Lecturer to Professor—demonstrates steady and significant advancement based on merit. His research focus on biosensors, food safety detection, magnetic relaxation sensors, and nanozyme-based immunoassays has led to high-impact publications in prestigious journals like ACS Sensors, Analyst, Analytical Chemistry, and Journal of Agricultural and Food Chemistry. Notably, many of his papers are published as first or corresponding author, reflecting his leadership in research projects. He has secured multiple national and provincial research grants totaling millions of RMB, notably presiding over projects under China’s National Key Research and Development Program. His ability to independently lead large-scale, cutting-edge research initiatives and translate them into real-world food safety applications highlights his excellence in innovation, scientific contribution, and societal impact.

🎓Education:

Dr. Zhou Xu began his academic journey with a Bachelor of Science (B.S.) degree in Biotechnology from Central South University of Forestry and Technology (2001–2005). He then pursued a Master of Science (M.S.) in Processing and Storage of Agricultural Products from the same university, graduating in 2009. Building on this strong foundation, Dr. Xu earned his Ph.D. in Food Nutrition and Safety (Physical Chemistry) from Jiangnan University in March 2013. His doctoral research focused on advanced methodologies for food quality assurance and safety analysis. Throughout his education, Dr. Xu consistently demonstrated excellence, laying the groundwork for a successful academic and research career. His interdisciplinary background spanning biotechnology, food science, and physical chemistry uniquely positions him to address complex issues at the intersection of food safety, nanotechnology, and biosensor development. His education equipped him with diverse skills crucial for his innovative contributions to food science research and technology.

🏢Work Experience:

Dr. Zhou Xu’s academic career began in January 2014 as a Lecturer at Changsha University of Science and Technology. His dedication and research achievements led to his promotion to Associate Professor in August 2018, and then to full Professor in January 2022. Currently, he also serves as the Assistant Dean of the School of Food Science and Bioengineering. Over the years, he has successfully led multiple major research projects funded by national and provincial agencies, focusing on intelligent food safety monitoring, rapid detection technologies, and biosensors. Dr. Xu’s professional journey reflects his strong leadership, mentorship of young researchers, and innovative project management. His deep expertise in bio sensing and nanomaterials has significantly advanced the field of food safety detection. Under his leadership, the university’s research capacity in biosensor technology has expanded greatly. He actively collaborates across disciplines to drive technological innovations addressing real-world food safety challenges.

🏅Awards: 

Dr. Zhou Xu has garnered numerous accolades throughout his illustrious career. He has been the recipient of the prestigious Fund for Excellent Youth of Hunan Province, recognizing his outstanding contributions to biosensor development for food safety (2022–2025). His projects have also secured significant funding from major national agencies, including the National Natural Science Foundation of China and the Natural Science Foundation of Hunan Province. Dr. Xu’s innovative work in food quality detection technologies has been praised for its practical impact and scientific excellence. His consistent success in obtaining competitive research grants highlights his reputation as a leading researcher in his field. Moreover, his work has earned him recognition in academic and government circles as a key contributor to the advancement of intelligent food safety monitoring systems. These awards and honors underline Dr. Xu’s exceptional dedication to scientific innovation, research excellence, and societal impact in the field of food science.

🔬Research Focus:

Dr. Zhou Xu’s research centers on the development of innovative biosensors and nanotechnology-based solutions for food safety detection. His work integrates magnetic relaxation switch sensors, nanozyme-based immunoassays, and metal-organic frameworks (MOFs) to enhance sensitivity and speed in detecting contaminants like aflatoxin B1, cadmium ions, and bisphenol A. By designing intelligent detection platforms based on the Internet of Things (IoT) and advanced materials, Dr. Xu aims to revolutionize food quality supervision and rapid analysis. His studies focus heavily on improving catalytic mechanisms, developing dual-mode immunosensors (fluorescence and magnetic sensing), and constructing biomimetic materials for enhanced assay performance. Through interdisciplinary collaborations, Dr. Xu bridges chemistry, biology, and material science to address major food safety challenges. His research not only advances academic knowledge but also directly impacts industrial practices and public health regulations. Dr. Xu is committed to pioneering practical, scalable technologies for real-time food safety monitoring.

Publication Top Notes:

1.Title: Alanine Substitution to Determine the Effect of LR5 and YR6 Rice Peptide Structure on Antioxidant and Anti-Inflammatory Activity

2.Title: Formation and Characterization of Self-Assembled Rice Protein Hydrolysate Nanoparticles as Soy Isoflavone Delivery Systems

3.Title: Target-modulated UCNPs-AChE assembly equipped with microenvironment-responsive immunosensor
Authors: Zhou Xu et al.

4.Title: Peroxidase-mimetic activity of a nanozyme with uniformly dispersed Fe₃O₄ NPs supported by mesoporous graphitized carbon for determination of glucose

5.Title: Three-dimensional assembly and disassembly of Fe₃O₄-decorated porous carbon nanocomposite with enhanced transversal relaxation for magnetic resonance sensing of bisphenol A

6.Title: Assembly of USPIO/MOF nanoparticles with high proton relaxation rates for ultrasensitive magnetic resonance sensing

7.Title: Metal Organic Frame-Upconverting Nanoparticle Assemblies for the FRET Based Sensor Detection of Bisphenol A in High-Salt Foods

8.Title: Extraction of antioxidant peptides from rice dreg protein hydrolysate via an angling method

9.Title: A nanozyme-linked immunosorbent assay based on metal-organic frameworks (MOFs) for sensitive detection of aflatoxin B₁

10.Title: Aptamer-enhanced fluorescence determination of bisphenol A after magnetic solid-phase extraction using Fe₃O₄@SiO₂@aptamer

11.Title: Recent Advances in Porphyrin-Based Materials for Metal Ions Detection

12.Title: Metal-Organic Frameworks of MIL-100(Fe, Cr) and MIL-101(Cr) for Aromatic Amines Adsorption from Aqueous Solutions

Assoc. Prof. Dr. cetin bayrak | Organic Chemistry | Best Researcher Award

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Assoc. Prof. Dr. cetin bayrak | Organic Chemistry | Best Researcher Award

Assoc. Prof. Dr. cetin bayrak , Agri Ibrahim Cecen University , Turkey

Dr. Çetin Bayrak is an Associate Professor at Ağrı İbrahim Çeçen University, Turkey. With a strong academic foundation in organic chemistry, he holds dual Bachelor’s degrees in Chemistry and Food Engineering from Atatürk University, where he also completed his MSc and PhD in Organic Chemistry. Dr. Bayrak’s research spans natural product synthesis, bromination, and mechanistic organic chemistry, focusing on biologically active molecules and enzyme inhibition studies. He has published extensively in top-tier journals and contributed to several high-impact research projects funded by TUBITAK. Dr. Bayrak has also been a visiting scholar with the Kozlowski Group, furthering his expertise in synthesis and catalysis. In addition to his academic accomplishments, he has presented at numerous international conferences, showcasing his innovative research. An expert in NMR spectroscopy and organic compound characterization, Dr. Bayrak’s work bridges fundamental organic chemistry and applied biological research.

Professional Profile

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Summary of Suitability for Award:

Dr. Çetin Bayrak is a distinguished academic and researcher with extensive contributions to the field of organic chemistry. He has demonstrated excellence in education, holding dual bachelor’s degrees in Chemistry and Food Engineering, and advanced degrees (M.Sc. and Ph.D.) from Atatürk University. His research career includes notable positions, such as Associate Professor and Assistant Professor at Ağrı İbrahim Çeçen University, and a visiting scholar experience that highlights his global scientific engagement. Dr. Çetin Bayrak is a highly suitable candidate for the “Best Researcher Awards” due to his significant academic achievements, impactful research contributions, and demonstrated commitment to advancing the field of organic chemistry. His innovative work and dedication make him a strong contender for this prestigious recognition.

🎓Education:

Dr. Çetin Bayrak completed his education at Atatürk University, Erzurum, Turkey. He earned a BSc in Chemistry (2004–2008) and a double major in Food Engineering (2005–2009). For postgraduate studies, he pursued an MSc in Organic Chemistry (2010–2013) and a PhD in Organic Chemistry (2013–2017). His research during this time laid a robust foundation in organic synthesis, with a focus on biologically active bromophenols and reaction mechanisms. His academic journey continued as an Assistant Professor at Ağrı İbrahim Çeçen University (2017–2024) and later as an Associate Professor (2024–present). From 2021 to 2023, Dr. Bayrak was a visiting scholar with the Kozlowski Group, where he advanced his expertise in triazole phosphines and catalytic applications. This diverse and rigorous academic training has shaped him into a leading researcher in organic and mechanistic chemistry, emphasizing biologically significant compound synthesis and enzyme activity studies.

🏢Work Experience:

Dr. Çetin Bayrak has a rich professional background in organic chemistry research and teaching. He began his academic career as an Assistant Professor at Ağrı İbrahim Çeçen University in 2017, where he was promoted to Associate Professor in 2024. From 2021 to 2023, he worked as a visiting scholar with the Kozlowski Group, focusing on triazole phosphines and catalytic applications. His extensive project experience includes significant contributions to TUBITAK-funded research, such as the first synthesis of biologically active bromophenols (Project 113Z702) and the total synthesis of Onosmon analogs (Project 119R034). Dr. Bayrak has presented his work at numerous national and international conferences, sharing insights into enzyme inhibition, molecular docking, and natural product synthesis. He is proficient in advanced characterization techniques like NMR, GCMS, and HPLC, showcasing a commitment to cutting-edge research in mechanistic and applied organic chemistry.

🏅Awards: 

Dr. Çetin Bayrak has received recognition for his groundbreaking contributions to organic chemistry. He was honored with funding through prestigious TUBITAK programs, including Project 2219 for his work on triazole phosphines and their catalytic applications (2021–2023). His projects, such as the first synthesis of biologically active bromophenols and the total synthesis of Onosmon analogs, highlight his innovative approach to natural product synthesis and catalysis. Dr. Bayrak’s consistent publication of high-impact research has earned him accolades within the scientific community, and his presentations at esteemed international conferences have further distinguished his academic career. These honors underscore his dedication to advancing the field of organic chemistry, with a particular focus on biologically significant compounds and their applications.

🔬Research Focus:

Dr. Çetin Bayrak’s research centers on organic synthesis, focusing on the development of biologically active molecules and natural product derivatives. His work includes bromination reactions, mechanistic organic chemistry, and enzyme inhibition studies. Dr. Çetin Bayrak has synthesized novel bromophenol compounds, characterized their biological activities, and explored their inhibitory effects on enzymes like carbonic anhydrase and aldose reductase. He is also proficient in molecular docking studies, elucidating enzyme-ligand interactions. Recent projects include developing triazole phosphines for selective oxidative addition and investigating their catalytic properties. With expertise in advanced analytical techniques like NMR and HPLC, Dr. Çetin Bayrak’s research contributes significantly to medicinal chemistry and material science, bridging theoretical and applied organic chemistry.

Publication Top Notes:

Title: The first synthesis, carbonic anhydrase inhibition, and anticholinergic activities of some bromophenol derivatives with S including natural products
Authors: C. Bayrak, P. Taslimi, H.S. Karaman, İ. Gülçin, A. Menzek
Citations: 139
Year: 2019

Title: The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase, and…
Authors: Ç. Bayrak, P. Taslimi, İ. Gülçin, A. Menzek
Citations: 135
Year: 2017

Title: The first synthesis and antioxidant and anticholinergic activities of 1-(4, 5-dihydroxybenzyl)pyrrolidin-2-one derivative bromophenols including natural products
Authors: M. Rezai, C. Bayrak, P. Taslimi, İ. Gülçin, A. Menzek
Citations: 87
Year: 2018

Title: Synthesis and rearrangement reactions of 1,4-dihydrospiro[1,4-methanonaphthalene-9,1′-cyclopropane] derivatives
Authors: C. Bayrak, H. Senol, S. Sirtbasi, E. Sahin, A. Menzek
Citations: 19
Year: 2018

Title: Cycloaddition reaction of spiro[2.4]hepta-4,6-dien-1-ylmethanol and PTAD: a new rearrangement
Authors: H. Şenol, C. Bayrak, A. Menzek, E. Şahin, M. Karakuş
Citations: 18
Year: 2016

Title: Synthesis and photophysical properties of new pyrazolines with triphenyl and ester derivatives
Authors: A.M. Şenol, Ç. Bayrak, A. Menzek, Y. Onganer, N. Yaka
Citations: 14
Year: 2020

Title: Synthesis and aldose reductase inhibition effects of celecoxib derivatives containing pyrazole linked-sulfonamide moiety
Authors: C. Bayrak
Citations: 10
Year: 2022

Title: The first synthesis of phenylpropanoid derivative bromophenols including natural products: Formation of an indene derivative compound
Authors: C. Bayrak, A. Menzek
Citations: 8
Year: 2020

Title: 1,3‐dipolar cycloaddition reactions of the compound obtained from cyclopentadiene‐PTAD and biological activities of adducts formed selectively
Authors: M.A. Yavari, P. Taslimi, C. Bayrak, T. Taskin‐Tok, A. Menzek
Citations: 7
Year: 2022

Title: Synthesis and biological activity of some bromophenols and their derivatives including natural products
Authors: C. Bayrak, P. Taslimi, N. Kilinc, I. Gulcin, A. Menzek
Citations: 6
Year: 2023

Dr. Hongjian Qin | Organic Chemistry | Best Researcher Award

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Dr. Hongjian Qin | Organic Chemistry | Best Researcher Award

Dr. Hongjian Qin , Shanghai Institute of Materia Medica, CAS , China

Dr. Hongjian Qin is an accomplished researcher in sustainable and green chemistry, with expertise in drug process development and medicinal administration. He earned his Ph.D. in Organic Chemistry from the Chinese Academy of Sciences, being recognized as an Excellent Graduate in 2024. Dr. Hongjian Qin’s contributions to the field span over three years, emphasizing environmentally friendly pharmaceutical synthesis and active pharmaceutical ingredient (API) development. Currently serving as Research Director at Topharman Company Limited, he continues to advance innovative solutions in drug development. His work includes mentoring students, enhancing resource recovery, and participating in COVID-19 research. With numerous impactful publications, Dr. Hongjian Qin is a dedicated professional committed to promoting sustainability and advancing solutions for global environmental challenges.

Professional Profile:

Scopus 

Summary of Suitability for Award:

Dr. Hongjian Qin is an exemplary candidate for the “Best Researcher Awards,” with a distinguished career in sustainable and green chemistry. His pioneering research in eco-friendly pharmaceutical synthesis has significantly contributed to reducing industrial waste and enhancing process efficiency, aligning with global sustainability objectives. Dr. Hongjian Qin’s innovative work on ligand-free catalysis, large-scale API production, and impurity profiling reflects his expertise in developing practical solutions for complex challenges in organic chemistry and medicinal chemistry. Dr. Hongjian Qin’s research excellence, innovative contributions, and global impact make him a highly deserving candidate for the “Best Researcher Awards.” His work not only addresses critical scientific challenges but also fosters sustainable practices in drug development, making a lasting impact on both academia and industry.

🎓Education:

Dr. Hongjian Qin holds a Ph.D. in Organic Chemistry from the Chinese Academy of Sciences , specializing in process development of drug substances and medicinal administration. His doctoral work was conducted at the Key Laboratory of Plant Resources and Chemistry in Arid Regions, showcasing expertise in sustainable pharmaceutical synthesis. He completed a Master of Engineering in Organic Chemistry from Guangxi University, focusing on the process development of drug substances. Dr. Qin’s academic journey began with a Bachelor of Science in Organic Chemistry from Guangxi University . His educational foundation combines rigorous theoretical knowledge with practical applications, preparing him to address complex challenges in green and sustainable chemistry.

🏢Work Experience:

Dr. Hongjian Qin’s professional journey spans over a decade, focusing on pharmaceutical synthesis and sustainable chemistry. As Research Director at Topharman Company Limited (2024–present), he spearheads innovations in active pharmaceutical ingredients (APIs) and emphasizes good manufacturing practices (GMP). Previously, as a Research Assistant at the Shanghai Institute of Materia Medica (2021–2024), he supported COVID-19 research projects, trained students, and enhanced pharmaceutical waste recovery techniques. At the Xinjiang Engineering Research Centre for Key Technologies and Processes of Ethnomedicine (2015–2021), Dr. Hongjian Qin led projects on sustainable API production and industrial resource recovery. His experiences reflect a blend of academic research and industrial application, driving advancements in pharmaceutical science.

🏅Awards: 

Dr. Hongjian Qin has received numerous accolades for his contributions to sustainable chemistry. He was honored as an Excellent Graduate in 2024 by the University of Chinese Academy of Sciences for his outstanding academic achievements during his Ph.D. studies. His work on sustainable pharmaceutical synthesis earned him recognition at various national and international conferences. Dr. Hongjian Qin has been instrumental in developing innovative processes for drug substances, garnering appreciation from industrial partners. Additionally, his mentorship roles and administrative contributions at research institutions have been commended, underscoring his commitment to advancing science and education.

🔬Research Focus:

Dr. Hongjian Qin’s research focuses on sustainable and green chemistry, particularly in the process development of drug substances. He has worked extensively on optimizing synthesis methods for pharmaceutical intermediates, reducing waste, and improving efficiency in drug manufacturing. His innovative approaches emphasize the use of eco-friendly reagents and catalysts, aligning with global sustainability goals. His recent work includes developing ligand-free copper-catalyzed cyclization methods, novel iron-catalyzed cross-coupling reactions, and efficient large-scale processes for active pharmaceutical ingredients (APIs). Dr. Hongjian Qin is dedicated to advancing environmentally responsible techniques in pharmaceutical synthesis, ensuring both industrial viability and ecological preservation.

Publication Top Notes:

1. Direct Esterification of Amides by the Dimethylsulfate-Mediated Activation of Amide C–N Bonds

Authors: Qin, H.; Han, Z.; Bonku, E.M.; Shen, J.; Aisa, H.A.

Year: 2024

Citations: 0

2. An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization

Authors: Odilov, A.; Gong, X.; Qin, H.; Yang, F.; Shen, J.

Year: 2024

Citations: 0

3. Impurity Study of Tecovirimat (Open Access)

Authors: Bonku, E.M.; Qin, H.; Odilov, A.; Wang, X.; Shen, J.

Year: 2024

Citations: 1

4. Improved and Ligand-Free Copper-Catalyzed Cyclization for an Efficient Synthesis of Benzimidazoles from o-Bromoarylamine and Nitriles (Open Access)

Authors: Bonku, E.M.; Qin, H.; Odilov, A.; Aisa, H.A.; Shen, J.

Year: 2024

Citations: 2

5. Direct Reductive N-Alkylation of Amines with Carboxylic Esters

Authors: Zhang, Y.; Bonku, E.M.; Yang, X.; Shen, J.; Qin, H.

Year: 2024 (In Press)

Citations: 0

6. Iron-Catalyzed Cross-Coupling Reactions of Alkyl Grignard Reagents with Alkenyl Carbonate

Authors: Qin, H.; Yang, X.; Mintah Bonku, E.; Shen, J.; Akber Aisa, H.

Year: 2024 (In Press)

Citations: 0

7. A Review of the Synthetic Strategies Toward the Antiviral Drug Tecovirimat (Review Article)

Authors: Bonku, E.M.; Qin, H.; Odilov, A.; Zhu, F.; Shen, J.

Year: 2024 (In Press)

Citations: 0

8. An Improved Iodine-Catalyzed Aromatization Reaction and Its Application in the Synthesis of a Key Intermediate of Cannabidiol

Authors: Abduahadi, S.; Bonku, E.M.; Qin, H.; Aisa, H.A.; Shen, J.

Year: 2024 (In Press)

Citations: 0

9. Optimized Synthesis of the Key Intermediate of Telmisartan via the Cyclization of 2-Bromoarylamine with n-Butyronitrile

Authors: Qin, H.; Mintah Bonku, E.; Odilov, A.; Zhu, F.; Aisa, H.A.

Year: 2023

Citations: 1

10. Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene

Authors: Bonku, E.M.; Qin, H.; Odilov, A.; Guma, S.D.; Shen, J.

Year: 2023

Citations: 4