Prof. Nehmé’s research centers on analytical sciences, particularly in capillary electrophoresis, mass spectrometry, and microscale thermophoresis for studying molecular interactions. Her projects frequently explore bioanalysis, enzyme kinetics, and natural product evaluation. She leads or participates in numerous ANR-funded projects, including stapled peptide design, bioremediation via micromycetes, and enzyme behavior in crowded synthetic environments. A significant part of her work involves developing lab-on-a-chip (LoC) platforms for investigating target-ligand interactions at the single-cell level. She has also contributed to the miniaturization of enzymatic assays, passive sampling techniques for water analysis, and electrochemical sensors for environmental monitoring. Prof. Nehmé integrates separation sciences with biology and materials chemistry, bridging analytical method development with real-world biological and environmental challenges. Her interdisciplinary research fosters innovations in diagnostics, therapeutic monitoring, and ecological risk assessment, marking her as a pioneer in translating analytical chemistry into functional tools for bioactive discovery and environmental stewardship.
Publication Top Notes:
1. Using CE to Confirm the Activity of Fluorescent miRFP670-LIMK1 Protein Produced for MST Assays Directly in Cell Lysate
2. The Antimicrobial Activity of ETD151 Defensin is Dictated by the Presence of Glycosphingolipids in the Targeted Organisms
3. Glycolipid and Lipopeptide Biosurfactants: Structural Classes and Characterization—Rhamnolipids as a Model
4. Nutraceutical and Cosmetic Applications of Bioactive Compounds of Saffron (Crocus Sativus L.) Stigmas and Its By-products
5. Antioxidant and Anti-lipase Capacities from the Extracts Obtained from Two Invasive Plants: Ambrosia artemisiifolia and Solidago canadensis
6. Nutraceutical Capacities of Extracts from the Invasive Plants Ambrosia artemisiifolia and Solidago canadensis
7. Screening and Evaluation of Dermo-Cosmetic Activities of the Invasive Plant Species Polygonum cuspidatum
8. Biosurfactant-Producing Mucor Strains: Selection, Screening, and Chemical Characterization
9. Capillary Electrophoresis for Enzyme-Based Studies: Applications to Lipases and Kinases
10. Correction to: Reproducibility and Accuracy of Microscale Thermophoresis in the NanoTemper Monolith: A Multi Laboratory Benchmark Study
11. Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors