Prof. Reine NEHME | Analytical Chemistry | Best Researcher Award

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Prof. Reine NEHME | Analytical Chemistry | Best Researcher Award

Prof. Reine NEHME, Analytical Chemistry , Head of analytical team at University of Orléans, ICOA UMR7311, France

Prof. Reine Nehmé is a renowned French scientist and Professor of Analytical Sciences at the University of Orléans, where she leads the “Analytical Strategies, Affinities and Bioactives” team at ICOA. With over 15 years of academic and research experience, she specializes in advanced separation techniques, bioanalysis, and microfluidics. She is deeply involved in both teaching and scientific governance—serving on multiple university and national scientific committees. Prof. Nehmé also contributes to scientific advancement as a supervisor of numerous Ph.D. and post-doctoral researchers and by coordinating key national research projects funded by ANR and regional bodies. Her prolific contributions to analytical chemistry are reflected in her numerous publications, particularly in the areas of enzymatic assays, capillary electrophoresis, and bioactive compound analysis. With a strong leadership role in Afsep and her involvement in high-level academic administration, she is recognized as a leading figure in analytical chemistry in France and Europe.

Professional Profile : 

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Summary of Suitability for Award:

Prof. Nehmé holds a Ph.D. in Analytical Chemistry from the University of Montpellier (2008) and an HDR (Accreditation toSupervise Research) from the University of Orléans (2016). Her academic background demonstrates deep expertise and a commitment to high-level scientific scholarship. As a professor and group leader at ICOA, University of Orléans, she leads the “Analytical Strategies, Affinities and Bioactives” team, driving impactful research in analytical sciences, especially in bioanalysis, separative techniques, capillary electrophoresis, microfluidics, and mass spectrometry. Prof. Nehmé is deputy treasurer and a management committee member of the Capillary Electrophoresis Group of Afsep. She holds leadership roles at her university and is actively engaged in curriculum design, evaluation panels, and scientific committees. Prof. Reine Nehmé exemplifies the ideal profile for a “Best Researcher Award”: a high-impact scientist, strategic research leader, dedicated educator, and committed scientific community member. Her strong publication record, funded projects, mentoring, and institutional service collectively highlight her as a trailblazer in analytical chemistry. She fully deserves recognition through such a prestigious award.

🎓Education:

Prof. Reine Nehmé earned her Ph.D. in Analytical Chemistry from the University of Montpellier in 2008, following her Master’s degree (Master 2) in the same field from the same institution in 2005. Demonstrating her continued academic excellence and expertise, she received her Habilitation to Supervise Research (HDR) from the University of Orléans in 2016. This qualification represents the highest academic degree in France and reflects her capacity to independently lead doctoral research and large-scale scientific projects. Her academic training laid a robust foundation in analytical methodologies, chromatographic techniques, and advanced spectroscopy. These qualifications have enabled her to contribute extensively to the development of innovative analytical tools and methods in environmental, biological, and pharmaceutical research. Her educational background not only established her scientific depth but also positioned her to take on leadership and mentoring roles across both academic and research platforms.

🏢Work Experience:

Prof. Nehmé began her academic journey at the University of Orléans in 2008 as a Temporary Teaching and Research Assistant (ATER). She advanced to Associate Professor in 2009 and was promoted to Professor in 2019. Over the years, she has held multiple leadership roles, including Head of the Analytical Chemistry Department and Coordinator of the Professional License program in Chemistry at IUT Chimie d’Orléans. She has been a member of the laboratory’s scientific council since 2017, and also serves on the Commission of Disciplinary Experts. As an active educator, she teaches a range of courses in analytical sciences including electrochemistry, chromatography, mass spectrometry, and microfluidics. In research, she has successfully supervised 6 Ph.D. students (2 ongoing) and multiple post-doctoral and master’s interns. Her contributions extend to national committees such as Afsep’s CE group, where she has served as Deputy Treasurer since 2021.

🏅Awards: 

While specific awards are not explicitly listed, Prof. Reine Nehmé’s honors are evidenced by her numerous leadership and elected roles. She received the Habilitation to Supervise Research (HDR), a distinguished recognition in France for scholarly excellence. Her long-standing position on the scientific council of the ICOA laboratory and as a Commission Expert in disciplinary affairs at the University of Orléans speaks to her academic credibility. She was elected to the Management Committee of the CE group of Afsep in 2017 and appointed as Deputy Treasurer in 2021, underlining national recognition by her peers. She has consistently been entrusted with leadership in nationally funded research programs by ANR and regional agencies, confirming her scientific standing and project leadership ability. Her active role in supervising doctoral candidates and international collaborations further affirms her status as a respected figure in analytical sciences.

🔬Research Focus:

Prof. Nehmé’s research centers on analytical sciences, particularly in capillary electrophoresis, mass spectrometry, and microscale thermophoresis for studying molecular interactions. Her projects frequently explore bioanalysis, enzyme kinetics, and natural product evaluation. She leads or participates in numerous ANR-funded projects, including stapled peptide design, bioremediation via micromycetes, and enzyme behavior in crowded synthetic environments. A significant part of her work involves developing lab-on-a-chip (LoC) platforms for investigating target-ligand interactions at the single-cell level. She has also contributed to the miniaturization of enzymatic assays, passive sampling techniques for water analysis, and electrochemical sensors for environmental monitoring. Prof. Nehmé integrates separation sciences with biology and materials chemistry, bridging analytical method development with real-world biological and environmental challenges. Her interdisciplinary research fosters innovations in diagnostics, therapeutic monitoring, and ecological risk assessment, marking her as a pioneer in translating analytical chemistry into functional tools for bioactive discovery and environmental stewardship.

Publication Top Notes:

1. Using CE to Confirm the Activity of Fluorescent miRFP670-LIMK1 Protein Produced for MST Assays Directly in Cell Lysate

2. The Antimicrobial Activity of ETD151 Defensin is Dictated by the Presence of Glycosphingolipids in the Targeted Organisms

3. Glycolipid and Lipopeptide Biosurfactants: Structural Classes and Characterization—Rhamnolipids as a Model

4. Nutraceutical and Cosmetic Applications of Bioactive Compounds of Saffron (Crocus Sativus L.) Stigmas and Its By-products

5. Antioxidant and Anti-lipase Capacities from the Extracts Obtained from Two Invasive Plants: Ambrosia artemisiifolia and Solidago canadensis

6. Nutraceutical Capacities of Extracts from the Invasive Plants Ambrosia artemisiifolia and Solidago canadensis

7. Screening and Evaluation of Dermo-Cosmetic Activities of the Invasive Plant Species Polygonum cuspidatum

8. Biosurfactant-Producing Mucor Strains: Selection, Screening, and Chemical Characterization

9. Capillary Electrophoresis for Enzyme-Based Studies: Applications to Lipases and Kinases

10. Correction to: Reproducibility and Accuracy of Microscale Thermophoresis in the NanoTemper Monolith: A Multi Laboratory Benchmark Study

11. Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors

 

 

Ola Saleh | Pharmaceutical Analytical Chemistry | Analytical Chemistry Award

Published on by Chemistry Awards

Prof. Ola Saleh| Pharmaceutical Analytical Chemistry | Analytical Chemistry Award

Professor at National Research Centre, Egypt 

Dr. Ola Ahmed Saleh is a distinguished professor at the Medicinal and Pharmaceutical Chemistry Department, National Research Centre, Cairo, Egypt. With extensive experience in pharmaceutical chemistry, she specializes in the synthesis of active pharmaceutical entities and the chiral separation of racemic drugs.

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Dr. Saleh’s research contributions have garnered significant recognition in the academic community, reflected in numerous citations and the impact of her work on pharmaceutical chemistry. Her publications are frequently referenced, underscoring her influence in the field.

  • Citations: 170 citations from 161 documents
  • Publications: 21 documents
  • h-index: 8

Education

Dr. Saleh holds a Bachelor’s degree in Pharmacy, followed by a Master’s and PhD in Pharmaceutical Chemistry. Her advanced degrees underscore her deep knowledge and expertise in her specialized field of study.

Research Focus

Dr. Saleh’s research focuses on synthesizing biologically active pharmaceutical entities. She has a particular interest in chiral separation and analyzing racemic drugs using high-performance liquid chromatography (HPLC), aiming to improve the efficacy and safety of pharmaceutical compounds.

Professional Journey

Dr. Saleh has a distinguished professional career marked by significant contributions to pharmaceutical chemistry. Her work spans various aspects of drug synthesis and analytical methods, establishing her as a leading figure in her field.

Honors & Awards

Throughout her career, Dr. Saleh has received numerous honors and awards, recognizing her exceptional contributions to pharmaceutical chemistry. These accolades highlight her dedication to research and her impact on the scientific community.

Publications Noted & Contributions

Dr. Saleh has an extensive publication record, with notable works in prestigious journals. Her research includes the synthesis of novel pharmaceutical compounds and the development of validated methods for drug analysis, contributing valuable knowledge to the field of pharmaceutical chemistry.

Title: A validated chromatographic method for simultaneous determination of guaifenesin enantiomers and ambroxol HCl in pharmaceutical formulation

  • Journal: RSC Advances
  • Year: 2015
  • DOI: 10.1039/c5ra19391e
  • EID: 2-s2.0-84946595298
  • Contributors: Saleh, O.A.; Yehia, A.M.; Abd-El Sattar El-Azzouny, A.; Aboul-Enein, H.Y.

Title: Synthesis and Anticonvulsant Activity of Substituted-1,3-diazaspiro[4.5]decan-4-ones

  • Journal: Archiv der Pharmazie
  • Year: 2015
  • DOI: 10.1002/ardp.201500092
  • EID: 2-s2.0-84938418531
  • Contributors: Aboul-Enein, M.N.; El-Azzouny, A.A.S.; Saleh, O.A.; Amin, K.M.; Maklad, Y.A.; Hassan, R.M.

Title: A validated high performance liquid chromatographic (HPLC) assay for nitazoxanide in bulk and in pharmaceutical formulations

  • Journal: Current Pharmaceutical Analysis
  • Year: 2014
  • DOI: 10.2174/1573412910666140506225012
  • EID: 2-s2.0-84904730253
  • Contributors: Saleh, O.A.; El-Azzouny, A.A.; Aboul-Enein, H.Y.; Badawey, A.M.

Title: Analysis of Stiripentol Enantiomers on Several Chiral Stationary Phases: A Comparative Study

  • Journal: Chromatographia
  • Year: 2014
  • DOI: 10.1007/s10337-014-2818-2
  • EID: 2-s2.0-84925489270
  • Contributors: Saleh, O.A.; El-Behairy, M.F.; Badawey, A.M.; El-Azzouny, A.A.; Aboul-Enein, H.Y.

Title: Riluzole: Validation of stability-indicating HPLC, D1 and DD1 spectrophotometric assays

  • Journal: Journal of Chromatographic Science
  • Year: 2014
  • DOI: 10.1093/chromsci/bmt062
  • EID: 2-s2.0-84902196955
  • Contributors: Saleh, O.A.; El-Azzouny, A.A.; Aboul-Enein, H.Y.; Badawey, A.M.

Research Timeline

Dr. Saleh’s research timeline spans over two decades, beginning in the late 1990s. Her sustained research efforts have continuously advanced the understanding of drug synthesis and analysis, contributing to the ongoing development of pharmaceutical science.

Collaborations and Projects

Dr. Saleh has collaborated extensively with researchers both locally and internationally. Her projects often involve interdisciplinary approaches, combining synthetic chemistry with advanced analytical techniques to address complex challenges in pharmaceutical research.

Recognition of Expertise in Analytical Chemistry

Dr. Ola Ahmed Saleh has been awarded the Analytical Chemistry Award in recognition of her outstanding contributions to the field. Her expertise spans various aspects of analytical chemistry, including method development, validation, and application in pharmaceutical analysis. Her work is distinguished by its rigorous approach to separation science, particularly in the enantioseparation of pharmaceutical compounds using advanced HPLC techniques.

Contributions to Method Development and Validation

Dr. Saleh’s research has significantly advanced the field through the development and validation of novel analytical methods. Notably, she has pioneered stability-indicating HPLC assays for a range of pharmaceutical compounds, ensuring accurate and reliable determination of drug purity and stability. Her methods have been widely adopted and cited in the scientific community, demonstrating their robustness and applicability in pharmaceutical quality control.

Impact on Pharmaceutical Analysis

Her work on enantioseparation using chiral stationary phases has provided critical insights into the stereochemical properties of drugs, influencing pharmacokinetic studies and therapeutic efficacy assessments. These contributions have enhanced our understanding of drug interactions and metabolism, crucial for optimizing drug formulations and patient outcomes.

Innovation in Chromatographic Techniques

Dr. Saleh’s innovative approaches in chromatographic techniques have been pivotal in addressing complex analytical challenges, such as simultaneous determination of multiple enantiomers and structurally similar compounds. Her research integrates experimental design optimization with computational modeling, pushing the boundaries of analytical chemistry capabilities.

Future Directions and Research Impact

Continuing her research trajectory, Dr. Saleh aims to explore new frontiers in analytical chemistry, particularly in green analytical methods and molecular docking studies. These efforts promise to advance sustainable analytical practices and deepen our understanding of molecular interactions in drug development.