Prof Dr. Joao Lago | Pharmacology | Best Researcher AwardĀ
Professor at Federal University of ABC, Brazil
Prof. Dr. Joao Henrique Ghilardi Lago is a distinguished researcher in Chemistry, specializing in the Chemistry of Natural Products. With extensive academic credentials including a Ph.D. from the University of SĆ£o Paulo and a background in both chemical education and research, he has made significant contributions to the field. His current position at the Federal University of ABC reflects his commitment to teaching and research in biosystems and organic chemistry. šæš¬ Dr. Lago’s work is marked by his leadership in various research projects focusing on the characterization and potential applications of specialized metabolites from Brazilian flora, particularly in combating neglected tropical diseases. His role as a grantee and reviewer for multiple scientific funding agencies underscores his influence and expertise in the scientific community, contributing to the advancement of bioorganic chemistry and pharmaceutical research in Brazil and beyond. š
Professional Profile:
Education
Prof. Dr. Joao Henrique Ghilardi Lago pursued a rigorous academic journey culminating in his esteemed position in the scientific community. He earned his Bachelor’s degree in Chemistry from the Federal University of Mato Grosso do Sul (UFMS), Brazil, before advancing to achieve a Master’s and Ph.D. in Chemistry from the University of SĆ£o Paulo (USP), one of Brazil’s leading institutions. š His doctoral research focused on natural products chemistry, a field he has since dedicated himself to with passion and expertise. Througho ut his educational path, Dr. Lago has demonstrated a commitment to excellence in scientific inquiry and a deep understanding of organic chemistry principles. His academic background has equipped him with the skills and knowledge to lead impactful research initiatives, particularly in the chemistry of natural products and their potential applications in medicine and pharmacology. šæš¬
Professional Experience
Prof. Dr. Joao Henrique Ghilardi Lago boasts a rich professional experience marked by significant contributions to the fields of chemistry and academia. He has held key positions such as a researcher and professor at the Federal University of Mato Grosso do Sul (UFMS), Brazil, where he has actively engaged in teaching and mentoring students while conducting groundbreaking research. š Dr. Lago’s research interests encompass natural products chemistry, medicinal chemistry, and synthetic organic chemistry, areas in which he has published numerous influential papers in prestigious scientific journals. His professional journey also includes collaborations with national and international research groups, fostering interdisciplinary approaches to tackle complex scientific challenges. As a recognized expert in his field, Dr. Lago continues to inspire and educate future generations of scientists through his dedicated work and leadership in academia. šš¬
Research Interest
Prof. Dr. Joao Henrique Ghilardi Lago’s research interests are centered around the fascinating realms of natural products chemistry, medicinal chemistry, and synthetic organic chemistry. šæ His work delves into the exploration and synthesis of bioactive compounds derived from natural sources, aiming to uncover their potential applications in medicine and related fields. Dr. Lago is particularly intrigued by the molecular structures of natural products and their intricate biological activities, seeking to elucidate mechanisms that could lead to the development of new therapeutic agents. His research encompasses a blend of innovative synthetic methodologies and biological evaluations, striving to bridge
Award and Honor
Prof. Dr. Joao Henrique Ghilardi Lago has received numerous awards and honors throughout his distinguished career, recognizing his outstanding contributions to the field of organic and medicinal chemistry. š His accolades highlight his exceptional research achievements, including prestigious fellowships and grants that have supported his innovative investigations in natural products chemistry and drug discovery. Dr. Lago’s work has been consistently recognized for its impact on advancing scientific knowledge and addressing critical challenges in pharmaceutical science. His dedication to excellence and pioneering research methodologies has earned him the respect of his peers and the admiration of the scientific community. These honors underscore Dr. Lago’s significant role in shaping the future of chemical research and his ongoing commitment to excellence in academia and beyond. š
Research Skills
Prof. Dr. Joao Henrique Ghilardi Lago is highly skilled in conducting rigorous and innovative research, showcasing a profound expertise in organic synthesis, natural products chemistry, and medicinal chemistry. š§Ŗ His research skills encompass the design and execution of complex synthetic pathways to access novel compounds of biological interest. Dr. Lago excels in applying state-of-the-art analytical techniques to characterize and elucidate the structures of synthesized molecules, ensuring precision and accuracy in his findings. His proficiency extends to conducting biological evaluations to assess the pharmacological potential and mechanisms of action of synthesized compounds, contributing to the advancement of drug discovery and development. Dr. Lago’s research prowess is underscored by his ability to integrate diverse scientific disciplines, fostering collaborations that enrich the scope and impact of his investigations. With a commitment to excellence and innovation, he continues to push the boundaries of chemical research, making significant contributions to the field. š
Publications
š2012
- Title: The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
- Journal: Current Medicinal Chemistry
- Citation: 375
- Authors: TJ Schmidt, SA Khalid, ĆJ Romanha, TMA Alves, MW Biavatti, R Brun, …
š2004
- Title: Benzoic Acid Derivatives from Piper Species and Their Fungitoxic Activity against Cladosporium cladosporioides and C. sphaerospermum
- Journal: Journal of Natural Products
- Citation: 271
- Authors: JHG Lago, CS Ramos, DCC Casanova, AA Morandim, DCB Bergamo, …
š2015
- Title: Antimicrobial activity of oleanolic and ursolic acids: an update
- Journal: Evidence-Based Complementary and Alternative Medicine
- Citation: 249
- Authors: JA Jesus, JHG Lago, MD Laurenti, ES Yamamoto, LFD Passero
š2011
- Title: Ī±-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model
- Journal: Biochemical and Biophysical Research Communications
- Citation: 234
- Authors: AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, …
š2014
- Title: Structure-activity association of flavonoids in lung diseases
- Journal: Molecules
- Citation: 218
- Authors: JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa, MA Martins, …
š2012
- Title: The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics
- Journal: Molecules
- Citation: 175
- Authors: JLB Zanin, BA De Carvalho, P Salles Martineli, MH Dos Santos, …
š2003
- Title: Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth
- Journal: Phytochemistry
- Citation: 171
- Authors: AP Danelutte, JHG Lago, MCM Young, MJ Kato
š2004
- Title: Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil
- Journal: Journal of Chromatography A
- Citation: 143
- Authors: S Aued-Pimentel, JHG Lago, MH Chaves, EE Kumagai
š2003
- Title: Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum
- Journal: Phytochemistry
- Citation: 138
- Authors: RCC Martins, JHG Lago, S Albuquerque, MJ Kato
š2012
- Title: In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC.(Asteraceae)
- Journal: Experimental Parasitology
- Citation: 132
- Authors: SS Grecco, JQ ReimĆ£o, AG Tempone, P Sartorelli, RLOR Cunha, …
š2007
- Title: Constituintes fenĆ³licos polares de Schinus terebinthifolius Raddi (Anacardiaceae)
- Journal: QuĆmica Nova
- Citation: 117
- Authors: M Ceruks, P Romoff, OA FƔvero, JHG Lago
š2015
- Title: Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo
- Journal: Biochemical and Biophysical Research Communications
- Citation: 107
- Authors: N Girola, CR Figueiredo, CF Farias, RA Azevedo, AK Ferreira, SF Teixeira, …
š2013
- Title: Flavonone treatment reverses airway inflammation and remodeling in an asthma murine model
- Journal: British Journal of Pharmacology
- Citation: 106
- Authors: AC Toledo, CPP Sakoda, A Perini, NM Pinheiro, RM Magalhaes, …
š2006
- Title: Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae)
- Journal: Phytochemistry
- Citation: 105
- Authors: ROS Kitamura, P Romoff, MCM Young, MJ Kato, JHG Lago
š2013
- Title: Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound Ī±-Zingiberene and Derivatives
- Journal: Molecules
- Citation: 101
- Authors: DD Bou, JHG Lago, CR Figueiredo, AL Matsuo, RC Guadagnin, …
š2006
- Title: Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth
- Journal: Phytochemistry
- Citation: 99
- Authors: LF Yamaguchi, JHG Lago, TM Tanizaki, P Di Mascio, MJ Kato
š2003
- Title: Antifungal aromadendrane sesquiterpenoids from the leaves of Xylopia brasiliensis
- Journal: Journal of the Brazilian Chemical Society
- Citation: 91
- Authors: IC Moreira, JHG Lago, MCM Young, NF Roque
š2011
- Title: Chemical and Biological Evaluation of Essential Oils from Two Species of Myrtaceae ā Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel
- Journal: Molecules
- Citation: 87
- Authors: JHG Lago, ED Souza, B Mariane, R Pascon, MA Vallim, RCC Martins, …
š2012
- Title: Essential oils from Schinus terebinthifolius leaves ā chemical composition and in vitro cytotoxicity evaluation
- Journal: Pharmaceutical Biology
- Citation: 86
- Authors: JS Santana, P Sartorelli, RC Guadagnin, AL Matsuo, CR Figueiredo, …
š2016
- Title: Evidences of herbal medicineāderived natural products effects in inflammatory lung diseases
- Journal: Mediators of Inflammation
- Citation: 82
- Authors: FPR Santana, NM Pinheiro, MIB Mernak, RF Righetti, MA Martins, …
š2002
- Title: Terpenoids from Guarea guidonia
- Journal: Phytochemistry
- Citation: 80
- Authors: JHG Lago, CB Brochini, NF Roque
š2016
- Title: Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase ā¦
- Journal: Phytomedicine
- Citation: 78
- Authors: C Vizetto-Duarte, L CustĆ³dio, KN Gangadhar, JHG Lago, C Dias, …
š2015
- Title: The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programmed Cell Death and Presents Therapeutic Potential in Experimental ā¦
- Journal: PLoS One
- Citation: 78
- Authors: ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti, SP Ribeiro, …
š2012
- Title: Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo
- Journal: PLoS One
- Citation: 76
- Authors: MH Massaoka, AL Matsuo, CR Figueiredo, CF Farias, N Girola, …