Gao Zhenzhen | Heterocycle Synthesis | Green Chemistry Award

Assoc. Prof. Dr. Gao Zhenzhen | Heterocycle Synthesis | Green Chemistry Award

Dean at Liaocheng University | China

Dr. Zhenzhen Gao is an Associate Professor at the School of Pharmacy and Food Engineering, Liaocheng University, China. She has been a faculty member at Liaocheng University since 2017, advancing from Lecturer to Associate Professor in 2025. Dr. Gao’s research lies at the intersection of synthetic organic chemistry and medicinal chemistry, with a focus on phosphine-catalyzed reactions and the development of biologically active molecules. She has published in reputable journals such as Molecules and International Journal of Molecular Sciences, contributing significant advancements in the synthesis of maleimide derivatives and their biological applications. She has successfully led a Shandong Provincial Natural Science Foundation General Project on the design and synthesis of α-allenoates with electron-withdrawing groups and novel cyclization reactions. Her work integrates chemical innovation with potential therapeutic value, bridging fundamental organic synthesis with applied pharmaceutical research. Dr. Gao is committed to advancing green, efficient, and biologically relevant synthetic methodologies.

Professional Profile

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Education 

Dr. Zhenzhen Gao holds advanced academic training in pharmaceutical and chemical sciences, having completed her higher education in China with a specialization in organic chemistry and drug synthesis. She developed a strong foundation in organic reaction mechanisms, catalysis, and structure–activity relationships during her postgraduate studies. Her academic journey emphasized both theoretical and experimental approaches, enabling her to work on designing and synthesizing functionalized organic compounds with potential biological activity. While formal education details are not specified, her expertise and publications reflect extensive training in synthetic methodologies, heterocyclic chemistry, and phosphine-catalyzed transformations. Dr. Gao’s education also involved collaborative research projects, where she gained experience with interdisciplinary teams combining chemistry, pharmacology, and materials science. This academic background has equipped her with the skills to develop innovative molecular scaffolds, optimize reaction conditions, and explore the medicinal potential of novel compounds—forming the basis of her later independent research career at Liaocheng University.

Experience 

Dr. Zhenzhen Gao began her academic career in July 2017 as a Lecturer at the School of Pharmacy and Food Engineering, Liaocheng University, where she contributed to teaching, curriculum development, and guiding undergraduate research. Over the next seven years, she expanded her research portfolio in organic synthesis, focusing on phosphine-catalyzed transformations and the synthesis of biologically relevant molecules. In January 2025, she was promoted to Associate Professor, recognizing her academic contributions and leadership in research. She has successfully led projects funded by the Shandong Provincial Natural Science Foundation, including the design and synthesis of α-allenoates with electron-withdrawing substituents and development of new cyclization methodologies. Dr. Gao’s professional experience combines innovative laboratory research with mentorship, academic service, and scholarly publishing. She collaborates with multidisciplinary teams to bridge chemical synthesis with pharmaceutical applications, contributing to advancements in both fundamental organic chemistry and applied medicinal chemistry.

Awards 

While no specific national or international awards are listed, Dr. Zhenzhen Gao’s professional achievements reflect significant academic recognition. Her promotion to Associate Professor at Liaocheng University in 2025 is a testament to her sustained research productivity, teaching excellence, and contribution to the university’s scientific standing. She has been entrusted with leading a competitive Shandong Provincial Natural Science Foundation General Project—an acknowledgment of her capability to conduct innovative, high-impact research. Her publications in high-quality, peer-reviewed journals such as Molecules and International Journal of Molecular Sciences demonstrate scholarly recognition from the scientific community. These achievements collectively serve as academic milestones, indicating her growing influence in the field of organic synthesis and medicinal chemistry. Through her leadership in funded projects, consistent publication record, and active involvement in academic activities, Dr. Gao has built a professional profile characterized by scientific rigor, innovation, and dedication to advancing chemical research.

Research Interests 

Dr. Zhenzhen Gao’s research interests center on synthetic organic chemistry, with a focus on phosphine-catalyzed reactions and the design of novel biologically active molecules. She specializes in the synthesis of α-allenoates containing electron-withdrawing substituents and the development of innovative cyclization methodologies. Her work explores the creation of functionalized heterocycles and maleimide derivatives, aiming to expand their potential in medicinal chemistry and pharmaceutical development. Dr. Gao is particularly interested in reaction mechanism elucidation, optimizing reaction efficiency, and achieving high selectivity in complex molecule synthesis. She also engages in studying structure–activity relationships (SAR) to understand how chemical modifications influence biological activity. By integrating synthetic strategies with biological evaluation, her research seeks to contribute to the development of new therapeutic agents. Additionally, she is interested in advancing green and sustainable chemistry practices, designing synthetic pathways that minimize environmental impact while maximizing chemical and pharmacological value.

Publication Top Notes

  • Title: Antifungal Activity and Multi-Target Mechanism of Action of Methylaervine on Candida albican
    Year: 2024 (June 24)

  • Title: Synthesis of 3,4-Disubstituted Maleimide Derivatives via Phosphine-Catalyzed Isomerization of α-Succinimide-Substituted Allenoates Cascade γ′-Addition with Aryl Imines
    Year: 2024

  • Title: Phosphine-Catalyzed γ′-Carbon 1,6-Conjugate Addition of α-Succinimide Substituted Allenoates with Para-Quinone Methides: Synthesis of 4-Diarylmethylated 3,4-Disubstituted MaleimidesYear: 2024 (May 31

Conclusion 

In summary, Dr. Zhenzhen Gao is an accomplished organic chemist whose career reflects a balance between innovative research and academic dedication. From her early role as a Lecturer to her promotion as Associate Professor, she has demonstrated consistent growth in scholarship, leadership, and project management. Her research on phosphine-catalyzed transformations and novel heterocyclic compounds bridges the gap between fundamental organic synthesis and potential medicinal applications. The successful execution of a Shandong Provincial Natural Science Foundation project underscores her capacity for impactful, funded research. Through publications in respected international journals, she has contributed valuable knowledge to the fields of synthetic methodology and medicinal chemistry.

 

Mrs. Mercedes Bertotto | Organic Chemistry | Women Researcher Award

Mrs. Mercedes Bertotto | Organic Chemistry | Women Researcher Award

Mrs. Mercedes Bertotto , Organic Chemistry , Researcher in Chemometrics at Wageningen University & Research , Netherlands

Dr. Mercedes Bertotto is a distinguished chemical engineer and food scientist with over 12 years of specialized experience in spectroscopic techniques, chemometrics, and quality control. Based in The Netherlands, she is currently a lecturer at Wittenborg University of Applied Sciences and founder of Vibralytics.nl, promoting sustainable and data-driven innovations in the agri-food sector. Previously, she was a researcher at Wageningen Food and Biobased Research, where she led spectral sensing projects integrating NIR, MIR, and Raman spectroscopy with machine learning. Her earlier role at SENASA, Argentina’s National Reference Laboratory, showcased her leadership in GC-MS residue analysis and chemometric modeling. Fluent in English, Spanish, and Dutch, Dr. Bertotto bridges scientific excellence with cross-cultural communication, driving sustainable solutions in food safety and circular materials. Her contributions to academia, research, and entrepreneurship reflect a strong commitment to innovation, international collaboration, and applied chemical sciences.

Professional Profile : 

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Scopus 

Summary of Suitability for Award:

Dr. Mercedes Bertotto stands out as an exceptionally qualified candidate for the “Women Researcher Award” due to her profound scientific expertise, leadership, and innovation across multiple sectors. With a Doctorate in Chemical Engineering and a strong academic foundation in Food Science and Technology, she exemplifies excellence in applied and theoretical research. Her 12+ years of impactful work—from Argentina’s SENASA National Reference Laboratory to the Netherlands’ Wageningen Food and Biobased Research—reflect her global research footprint. She has made significant contributions in spectral sensing, chemometrics, machine learning, and food quality control. Moreover, her entrepreneurial initiative as the founder and CEO of Vibralytics.nl demonstrates her commitment to translating science into real-world, sustainable solutions. Dr. Mercedes Bertotto is highly suitable for the “Women Researcher Award’. Her multidisciplinary achievements, pioneering role in spectral analytics, dedication to sustainable food systems, and entrepreneurial leadership in a male-dominated field exemplify the qualities the award seeks to recognize. Her career reflects not only scientific merit but also her inspirational impact as a woman in science, making her a deserving and empowering candidate for this honor.

🎓Education:

Dr. Bertotto holds a Doctorate in Chemical Engineering from the University of Buenos Aires, where her thesis focused on modeling drying and tempering processes of rice (IRGA 424). Her research included dynamic mechanical analysis and mathematical modeling of glass transition temperature, achieving an outstanding score of 10/10. She also holds a Master’s in Food Science and Technology from the Faculty of Pharmacy and Biochemistry, University of Buenos Aires. Her academic formation enabled her to work on food preservation, quality control, and raw material analysis using both physical and chemical techniques. Her educational foundation is rooted in experimental precision, mathematical rigor, and industrial application. This robust background has allowed her to seamlessly bridge theory with practical laboratory and industry-based problem-solving. Her education reflects interdisciplinary training, combining engineering, food science, and analytical chemistry—providing her with the ideal base for impactful research in sustainable biobased materials and food safety.

🏢Work Experience:

Dr. Bertotto brings an extensive and diverse professional background. She currently lectures in Information Management and Data Analytics at Wittenborg University and leads Vibralytics.nl, a company pioneering AI-driven spectroscopy for agri-food applications. Between 2022–2024, she was a spectral sensing researcher at Wageningen Food and Biobased Research, using hyperspectral imaging and chemometrics (PCA, PLS, CNN) for quality control. From 2010 to 2022, she worked at SENASA in Argentina, specializing in NIR/FTIR microscopy, GC-MS, and regulatory compliance in food safety. As a university professor, she taught chemometric tools for doctoral candidates, and she also served as a consultant at SoftLab, contributing to petroleum industry applications of NIR. Her expertise encompasses spectroscopy hardware (Specim FX10/17, MicroNIR, LabSpec), data tools (R, MATLAB), and AI-based modeling. This blend of research, teaching, and consulting makes her a well-rounded scientist, with real-world and academic impact across multiple industries.

🏅Awards: 

While specific awards are not explicitly listed, Dr. Mercedes Bertotto’s recognitions include multiple peer-reviewed publications, oral and poster presentations at prestigious conferences, and leadership roles in top-tier research institutions like Wageningen University. Her work was accepted for presentation at the 38th EFFoST International Conference (2024) and ICNIRS 2023, both internationally acclaimed events in food science and spectroscopy. She has also contributed to publicly recognized innovation efforts in Argentina, featured in national science communications (e.g., Argentina.gob.ar and API-Portal). Her appointment as a doctoral-level professor and selection as a founder and CEO of a research-driven company demonstrates academic and entrepreneurial recognition. Moreover, her trilingual fluency and international engagement serve as indicators of her global scientific outreach and influence. These distinctions—academic, institutional, and professional—reflect her commitment to innovation, research excellence, and interdisciplinary problem-solving in chemical engineering and food safety.

🔬Research Focus:

Dr. Bertotto’s research is grounded in analytical chemistry, spectral sensing, and chemometric modeling applied to food and agricultural systems. Her focus lies in leveraging Near-Infrared (NIR), Mid-Infrared (MIR), FTIR microscopy, Raman spectroscopy, and gas chromatography-mass spectrometry (GC-MS) to improve food quality, detect contaminants, and enable circular and sustainable material flows. She specializes in multivariate analysis (PCA, PLS-DA, ANN, CNN) for interpreting complex spectral data in real-time monitoring systems. Her work integrates hyperspectral imaging with AI-driven tools to predict physical and chemical properties of biological materials, such as fungal susceptibility in tomatoes or nutrient profiling in dairy. She is also deeply involved in modeling moisture and thermal behavior in grains like rice. Her research bridges fundamental science with applied industry solutions—creating novel analytical frameworks that optimize safety, quality, and sustainability in bio-based materials, food systems, and environmental monitoring.

Publication Top Notes:

1. Predicting fungal infection sensitivity of sepals in harvested tomatoes using imaging spectroscopy and partial least squares discriminant analysis

2. Comparison between Chemometrics and Machine Learning for the Prediction of Macronutrients in Fresh Cheeses Using Imaging Spectroscopy

3. Detection of Animal By‑Products in Bone Ashes by Near Infrared Spectroscopy Coupled with Microscopy

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