Assoc. Prof. Dr. Yue-Jin Liu | Organic Chemistry | Hubei University ,China
Dr. Yue-Jin Liu is an Associate Professor at Hubei University, specializing in organic chemistry and catalytic transformations. His research primarily focuses on developing novel methodologies for inert chemical bond activation, particularly carbon-hydrogen (C–H) bond functionalization. Dr. Liu has made significant contributions to the field by designing innovative strategies for multi-component reactions, paving the way for more efficient synthesis of biologically active molecules and functional organic compounds. His recent work on ruthenium-catalyzed remote C–H functionalization of naphthalenes has been widely recognized. Dr. Liu has published in leading journals such as Chemical Science, contributing valuable insights to the scientific community. Despite his intensive academic engagements, he continues to explore new synthetic strategies that promote sustainable and green chemistry approaches. Dr. Liu’s dedication to advancing organic synthesis has established him as an emerging expert in the field, with an ever-growing impact on modern synthetic methodologies.
Professional Profile :
Orcid
Scopus
Summary of Suitability for Award:
Dr. Yue-Jin Liu’s research focuses on developing novel organic synthesis methods with an emphasis on C–H bond activation, a key aspect of green chemistry. His work on ruthenium-catalyzed three-component reactions enables efficient, modular, and atom-economical synthesis of multifunctional naphthalenes. This aligns with green chemistry principles by minimizing waste, reducing the need for hazardous reagents, and enhancing reaction efficiency. His catalyst-driven methodologies promote sustainable chemical transformations, making his research highly relevant to the Green Chemistry Award category. Dr. Yue-Jin Liu’s contributions to sustainable organic synthesis through C–H activation strategies make him a strong contender for the “Green Chemistry Award”. His work reduces environmental impact by utilizing direct functionalization approaches, avoiding toxic reagents, and increasing efficiency in organic synthesis. These advancements have significant implications for eco-friendly chemical manufacturing, supporting global sustainability goals.
🎓Education:
Dr. Yue-Jin Liu pursued his higher education in organic chemistry, focusing on advanced synthesis and catalysis. He obtained his Bachelor’s, Master’s, and Ph.D. degrees from prestigious institutions where he specialized in carbon-hydrogen bond activation and synthetic methodologies. His doctoral research laid the foundation for his career, emphasizing transition-metal-catalyzed organic transformations. During his academic journey, Dr. Liu worked under the guidance of renowned chemists, gaining expertise in molecular design, reaction mechanisms, and green synthetic approaches. Throughout his education, he engaged in multiple research projects that contributed to the development of new catalytic systems. His commitment to innovation and excellence in organic synthesis has led him to a successful career in academia, where he continues to mentor students and advance research in C–H activation. His strong academic background serves as the backbone of his contributions to the field of organic and medicinal chemistry.
🏢Work Experience:
Dr. Yue-Jin Liu currently serves as an Associate Professor at Hubei University, where he focuses on organic synthesis and catalysis. With years of experience in developing new methodologies for carbon-hydrogen bond activation, he has contributed significantly to green chemistry and efficient molecular synthesis. His expertise extends to transition-metal catalysis, multi-component reactions, and synthetic applications in biologically active molecules. Dr. Liu has led several research projects, including the ruthenium-catalyzed three-component tandem remote C–H functionalization of naphthalenes, which has enhanced the efficiency of modular synthesis. Beyond academia, he actively collaborates with researchers worldwide, contributing to high-impact publications in Chemical Science. His commitment to teaching and mentoring young researchers has shaped the next generation of scientists in organic chemistry. Dr. Liu’s extensive experience in synthetic methodologies continues to drive forward the boundaries of modern organic transformations.
🏅Awards:
Dr. Yue-Jin Liu’s groundbreaking work in organic synthesis and catalysis has earned him recognition in the scientific community. His research on C–H activation strategies has been cited extensively, reflecting his contributions to green chemistry and innovative molecular synthesis. In 2025, he was nominated for the Green Synthesis Award for his pioneering work on ruthenium-catalyzed multi-component reactions. His publications in top-tier journals like Chemical Science have solidified his reputation as an emerging leader in organic chemistry. Despite his focus on fundamental research, Dr. Liu’s methodologies have practical applications in pharmaceutical synthesis and materials chemistry, earning him academic accolades. He continues to strive for excellence, pushing the boundaries of modern synthetic techniques and contributing to sustainable chemical transformations. His commitment to innovation and environmental responsibility has positioned him as a rising figure in green and sustainable chemistry.
🔬Research Focus:
Dr. Yue-Jin Liu’s research is dedicated to developing novel strategies for carbon-hydrogen (C–H) bond activation, aiming to create efficient, sustainable, and selective organic transformations. His work emphasizes multi-component reactions (MCRs), enabling the synthesis of complex molecular frameworks with high atom economy. A significant part of his research involves ruthenium-catalyzed tandem remote C–H functionalization, which facilitates the modular and concise synthesis of multifunctional naphthalenes. His studies contribute to green chemistry, reducing the need for harsh reagents and wasteful synthetic steps. Dr. Liu also explores transition-metal catalysis and ligand-controlled selectivity, expanding the scope of synthetic methodologies for biologically active compounds. His innovative approaches have potential applications in drug discovery, materials science, and fine chemical production. By integrating computational chemistry and experimental design, he continuously seeks to enhance reaction efficiency, selectivity, and sustainability in modern organic synthesis.
Publication Top Notes:
Cobalt(II)-Catalyzed Selective C2–H Heck Reaction of Native (N–H) Indoles Enabled by Salicylaldehyde Ligand
Salicylaldehyde-Enabled Co(II)-Catalyzed Oxidative C–H Alkenylation of Indoles with Olefins
Ruthenium-Catalyzed Three-Component Tandem Remote C–H Functionalization of Naphthalenes: Modular and Concise Synthesis of Multifunctional Naphthalenes
Mild C−H Alkoxylation of Aromatic Amides Catalyzed by Salicylaldehyde‐Co(II) Complexes
Cobalt/Salicylaldehyde-Enabled C–H Alkoxylation of Benzamides with Secondary Alcohols under Solvothermal Conditions
Salicylaldehyde-Cobalt(II)-Catalyzed C–H Alkoxylation of Indoles with Secondary Alcohols
Selective Synthesis of Sulfonamides and Sulfenamides from Sodium Sulfinates and Amines
Rapid Modular Synthesis of Indole Ethers via Dehydrogenative Cross-Coupling Reaction of Indoles and Alcohols
Remote C5-Selective Functionalization of Naphthalene Enabled by P–Ru–C Bond-Directed δ-Activation
Ru(II)-Catalyzed P(III)-Assisted C8-Alkylation of Naphthphosphines
Ruthenium-Catalyzed Meta-Difluoromethylation of Arene Phosphines Enabled by 1,3-Dione
Salicylaldehyde-Promoted Cobalt-Catalyzed C–H/N–H Annulation of Indolyl Amides with Alkynes: Direct Synthesis of a 5-HT3 Receptor Antagonist Analogue