György Keglevich is a distinguished chemist specializing in organophosphorus chemistry. He is a Full Professor at the Department of Organic Chemistry and Technology at Budapest University of Technology and Economics. With a career spanning several decades, Keglevich has made significant contributions to the field through his research, publications, and mentoring of future scientists. His work encompasses a wide range of topics in chemical synthesis, green chemistry, and practical applications of his research.

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György Keglevich is a prominent researcher affiliated with the Budapest University of Technology and Economics in Budapest, Hungary. He has made significant contributions to the field, with a notable citation count of 9,463 across 590 documents. His h-index is 43, reflecting the impact and influence of his work in the academic community.

Education

Keglevich graduated from the Technical University of Budapest (TUB) in 1981 with a degree in chemical engineering. He obtained his PhD and Doctor of Chemical Science degrees in organophosphorus chemistry and earned his “Dr Habil.” degree in 1995. His early academic career included research at Duke University under the guidance of Professor Louis D. Quin.

Research Focus

Keglevich’s research primarily revolves around organophosphorus chemistry, including the development of P-heterocyclic compounds, ring enlargement of five-membered P-heterocycles, and the synthesis of bridged P-heterocycles. His work also explores the reactivity of aromatic phospholes, phosphine-transition metal complexes, and green chemistry practices such as microwave-assisted reactions and the use of ionic liquids.

Professional Journey

Keglevich began his career as a research employee at the Chinoin Pharmaceutical Factory before joining TUB’s Department of Organic Chemical Technology as an Assistant Professor in 1982. He was promoted to Associate Professor in 1993 and became a Full Professor in 1996. He has held leadership roles within his department, including serving as Head from 1999 to 2021. He has also been a Visiting Associate Professor at the University of Massachusetts on multiple occasions.

Honors & Awards

Keglevich has received several prestigious awards, including the Award of the Hungarian Academy of Sciences in 2004. In 2021, he was honored with the state decoration of Knight-Cross for Hungarian Order, and in 2022, he received the József Palatine Prize from Budapest University of Technology. These accolades recognize his significant contributions to the field of chemistry.

Publications Noted & Contributions

Keglevich has made substantial contributions through his publications, which include around 651 papers, 51 book chapters, and two books. His research is noted for advancements in the Hirao reaction, catalyst-free P–C coupling reactions, and microwave-assisted direct esterification. His contributions have been influential in developing new methods and applications in chemistry.

N-Functionalization of β-Aminophosphonates: Cytotoxic Effects of the New Derivatives

Journal: Organic & Biomolecular Chemistry

Year: 2024

DOI: 10.1039/D4OB00243A

Contributors: György Keglevich, Petra Regina Varga, Emőke Dinnyési, Zsuzsanna Szalai, Szilvia Bősze, Oláhné Szabó Rita, László Drahos, Konstantin Karaghiosoff

Synthesis of Mesylated and Tosylated α-Hydroxy-Benzylphosphonates; Their Reactivity and Cytostatic Activity

Journal: ACS Omega

Date: July 16, 2024

DOI: 10.1021/acsomega.4c04382

Contributors: Zsuzsanna Szalai, Márton Debrei, Péter Ábrányi-Balogh, Szilvia Bősze, Rita Oláhné Szabó, Konstantin Karaghiosoff, László Drahos, György Keglevich

Microwave-Assisted, Ionic Liquid-Catalyzed Aminolysis and Alcoholysis of Phosphinic Derivatives: The Interconversion of Phosphinates and Phosphinic Amides

Journal: Green Chemistry

Year: 2023

DOI: 10.1039/D3GC02711B

Contributors: György Keglevich, Nikoletta Harsági, Sarolta Szilágyi

New N-Acyl- as well as N-Phosphonoylmethyl- and N-Phosphinoylmethyl-α-Amino-Benzylphosphonates by Acylation and a Tandem Kabachnik–Fields Protocol

Journal: Organic & Biomolecular Chemistry

Year: 2023

DOI: 10.1039/D3OB00010A

Contributors: Petra Regina Varga, Konstantin Karaghiosoff, Éva Viktória Sári, András Simon, László Hegedűs, László Drahos, György Keglevich

Synthesis and Anticancer Activity of Phosphinoylated and Phosphonoylated N-Heterocycles Obtained by the Microwave-Assisted Palladium Acetate-Catalyzed Hirao Reaction

Journal: Chemistry – A European Journal

Date: December 6, 2023

DOI: 10.1002/chem.202302465

Contributors: Bianka Huszár, Renáta Szolga, Szilvia Bősze, Rita Oláhné Szabó, András Simon, Konstantin Karaghiosoff, Mátyás Czugler, László Drahos, György Keglevich

Research Timeline

Keglevich’s research career began in the early 1980s with a focus on chemical synthesis and organophosphorus chemistry. Over the decades, he has developed and refined methodologies in green chemistry and practical applications. His research timeline includes significant milestones such as his promotion to Full Professor in 1996 and his ongoing work in innovative chemistry practices.

Collaborations and Projects

Keglevich has collaborated on numerous projects related to organophosphorus chemistry and green chemistry. His industrial projects include the synthesis of pharmaceutical intermediates and products, which are reflected in his three patents. He has also engaged in various academic collaborations, contributing to advancements in both theoretical and practical aspects of chemistry.

György Keglevich has authored or co-authored approximately 651 papers, including 51 book chapters and two books. His research output has earned him an h-index of 48, reflecting his significant impact in the field of chemistry. His publications are highly regarded, indicating a strong influence in organophosphorus and green chemistry research.

Strengths of the Green Chemistry Award for Prof. Dr. György Keglevich

1. Significant Contributions to Green Chemistry: Prof. Keglevich’s research emphasizes green chemistry practices, including microwave-assisted reactions and the use of ionic liquids. These contributions align well with the principles of green chemistry, aiming to make chemical processes more sustainable and environmentally friendly.
2. Innovative Methodologies: His work on catalyst-free P–C coupling reactions, microwave-assisted esterification, and ionic liquid-catalyzed reactions demonstrates a commitment to developing new, more efficient, and eco-friendly chemical processes.
3. Extensive Publication Record: With over 651 papers and numerous contributions to high-impact journals, Prof. Keglevich’s extensive publication record showcases his deep engagement with and impact on the field of green chemistry.
4. High Citation Count: An h-index of 48 and a citation count of 9,463 indicate that his research is highly influential and well-regarded within the academic community. This metric underscores the relevance and importance of his work in advancing green chemistry.
5. Recognition and Awards: The numerous awards and honors, including the Knight-Cross for Hungarian Order and the József Palatine Prize, affirm his significant impact and contributions to chemistry, reinforcing his candidacy for the Green Chemistry Award.

Areas for Improvement

1. Broader Impact on Industry: While Prof. Keglevich’s research is highly influential academically, showcasing a broader impact on industrial applications could strengthen his case for the Green Chemistry Award. Highlighting how his methodologies have been adopted or commercialized would be beneficial.
2. Integration with Emerging Green Technologies: There could be a more explicit connection to emerging green technologies such as renewable energy solutions or advanced recycling methods. Emphasizing how his work integrates with or contributes to these areas might enhance his profile.
3. Interdisciplinary Collaborations: Expanding collaborations beyond organophosphorus chemistry to include other disciplines such as materials science or environmental engineering could demonstrate a more comprehensive approach to solving green chemistry challenges.
4. Public Engagement and Outreach: Increasing efforts in public engagement, science communication, and education could further highlight the societal impact of his research. Showcasing initiatives that aim to educate and inspire the next generation of chemists could add value.
5. Future Research Directions: Outlining specific future research directions and how they align with the evolving goals of green chemistry could provide a forward-looking perspective. This might include exploring new green solvents, reaction conditions, or sustainable practices.

Conclusion

Prof. Dr. György Keglevich is a leading figure in green chemistry with a distinguished record of innovative research, extensive publications, and significant contributions to sustainable chemical practices. His work on eco-friendly methodologies and high-impact research underscores his qualifications for the Green Chemistry Award. Addressing areas for improvement, such as demonstrating broader industrial impact and engaging with emerging green technologies, could further strengthen his candidacy. Overall, his accomplishments and recognition in the field make him a strong contender for the award, reflecting his dedication to advancing green chemistry and its practical applications.