Prof. Dr. Hauh-Jyun Chen | Environmental Chemistry | Best Researcher Award

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Prof. Dr. Hauh-Jyun Chen | Environmental Chemistry | Best Researcher Award

Prof. Dr. Hauh-Jyun Chen | Environmental Chemistry | Dept Chemistry and Biochemistry at National Chung Cheng University , Taiwan 

Dr. Hauh-Jyun Candy Chen is a Distinguished Professor in the Department of Chemistry and Biochemistry at National Chung Cheng University, Taiwan. She is a leading expert in organic chemistry, chemical carcinogenesis, and mass spectrometric analysis of biomolecules. Dr. Chen earned her Ph.D. in Organic Chemistry from the State University of New York at Stony Brook in 1988 under the supervision of Professor Iwao Ojima. Her research focuses on using mass spectrometry for biomarker identification in cancer and oxidative stress-related diseases. She has made significant contributions to understanding post-translational modifications in hemoglobin and DNA, particularly in relation to cigarette smoking and carcinogen exposure. Dr. Chen has held various academic and research positions in the U.S. and Taiwan, including at the American Health Foundation and the National Institutes of Health. She has published extensively in high-impact journals and is recognized internationally for her pioneering work in analytical toxicology.

Professional Profile : 

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Summary of Suitability for Award:

Professor Hauh-Jyun Candy Chen is an outstanding researcher in the field of organic chemistry and biochemical research, with a strong focus on mass spectrometry-based biomonitoring, chemical exposome analysis, and biomarker identification related to cancer and smoking-related diseases. Her academic credentials, extensive research experience, and significant scientific contributions make her a strong candidate for the “Best Researcher Award. “Professor Hauh -J yun Candy Chen’s distinguished career, pioneering research in biomolecular analysis, and commitment to scientific advancements in chemistry and biochemistry make her an exceptional candidate for the “Best Researcher Award.” Her work not only deepens the understanding of chemical exposures and their health effects but also has significant translational potential in clinical diagnostics and public health. Given her research impact, leadership in the field, and continuous contributions to high-quality publications, she is highly suitable for this prestigious recognition.

🎓Education:

Dr. Hauh-Jyun Candy Chen completed her Ph.D. in Organic Chemistry at the State University of New York at Stony Brook in 1988. Her dissertation, titled New and Effective Routes to Optically Pure Aromatic Amino Acids, Peptides, and Their Derivatives via Chiral β-Lactam Intermediates, was conducted under the guidance of Professor Iwao Ojima. She earned her Bachelor of Science degree in Chemistry from National Cheng Kung University, Taiwan, in 1983. Dr. Chen’s academic training provided her with a strong foundation in organic synthesis, bioanalytical chemistry, and mass spectrometry. Her interdisciplinary expertise has allowed her to develop innovative methodologies for studying chemical modifications in biomolecules, particularly in relation to disease biomarkers and environmental toxicology. Throughout her career, Dr. Chen has continuously expanded her research scope, integrating advanced analytical techniques to investigate the biochemical impacts of carcinogens, oxidative stress, and metabolic disorders.

🏢Work Experience:

Dr. Hauh-Jyun Candy Chen has over three decades of research and teaching experience in organic chemistry and bioanalytical sciences. She has been a Distinguished Professor at National Chung Cheng University since 2020, where she previously served as Professor (2004-2020), Associate Professor (1999-2004), and Assistant Professor (1997-1999). Before joining academia, she was an Associate Research Scientist at the American Health Foundation (1994-1997), where she worked on nucleic acid chemistry and chemical carcinogenesis. From 1992 to 1994, she was a Senior Research Fellow at the same institution. She also conducted postdoctoral research at the Rockefeller University (1989-1991), the Picower Institute for Medical Research (1991), and the National Institutes of Health (1988-1989). Her extensive research in analytical toxicology and mass spectrometry has advanced the understanding of oxidative and carcinogenic modifications in biomolecules, leading to breakthroughs in biomarker discovery for cancer and exposure assessment.

🏅Awards: 

Dr. Hauh-Jyun Candy Chen has received numerous awards and recognitions for her outstanding contributions to analytical chemistry and toxicology. Her research on post-translational modifications in hemoglobin and the development of mass spectrometric methodologies has been widely recognized. She has been invited to present at international conferences on biomolecular analysis and chemical carcinogenesis. Dr. Chen has received multiple research grants from prestigious funding agencies, reflecting the impact and significance of her work. Her publications in high-impact journals have garnered substantial citations, further establishing her as a leading figure in analytical toxicology. As a dedicated mentor, she has supervised numerous graduate students and postdoctoral researchers, many of whom have gone on to successful academic and industry careers. Her contributions to environmental health, biomarker discovery, and disease diagnostics continue to shape the field of chemical research and biomedical science.

🔬Research Focus:

Professor Hauh-Jyun Candy Chen’s research primarily focuses on the analysis of chemical exposures and their impact on human health using advanced mass spectrometry techniques. Her work emphasizes the identification and quantification of biomarkers for diseases linked to environmental and lifestyle factors, particularly in the context of cancer and smoking-related illnesses. A significant part of her research explores oxidative and post-translational modifications in proteins, such as hemoglobin, resulting from exposure to toxic chemicals like acrolein and malondialdehyde. Through high-resolution mass spectrometry, Professor Chen investigates how these modifications can serve as biomarkers for disease diagnosis and progression, particularly in cancer patients and smokers. Her research also includes studies on the chemical exposome, connecting environmental exposures to human health outcomes. With a focus on precision biomonitoring and toxicology, her work aims to improve disease prevention, early detection, and therapeutic strategies, providing valuable insights into the relationship between chemical exposures and chronic diseases.

Publication Top Notes:

Multiple Oxidative Modifications on Hemoglobin Are Elevated in Breast Cancer Patients as Measured by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry

Authors: H.J.C. Chen, Hauh Jyun Candy; S. Hu, Shunxiang; C. Tu, Chiwen

Year: 2025

Citations: 0

Connecting Chemical Exposome to Human Health Using High-Resolution Mass Spectrometry-Based Biomonitoring: Recent Advances and Future Perspectives

Authors: Y. Chen, Yuanchieh; J.F. Hsu, Jing Fang; C. Chang, Chihwei; H.J.C. Chen, Hauh Jyun Candy; P. Liao, Pao-Chi

Year: 2023

Citations: 15

Response to “Malondialdehyde-Induced Post-Translational Modification of Human Hemoglobin”

Authors: H.J.C. Chen, Hauh Jyun Candy; Y. Liao, Yanling

Year: 2023

Citations: 0

Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example

Authors: H.J.C. Chen, Hauh Jyun Candy

Year: 2023

Citations: 15

Characterization and Quantification of Acrolein-Induced Modifications in Hemoglobin by Mass Spectrometry─Effect of Cigarette Smoking

Authors: H.J.C. Chen, Hauh Jyun Candy; S. Cheng, Shuwei; N. Chen, Naiying; D. Wu, Dengchyang

Year: 2022

Citations: 6

Malondialdehyde-Induced Post-translational Modifications in Hemoglobin of Smokers by NanoLC-NSI/MS/MS Analysis

Authors: H.J.C. Chen, Hauh Jyun Candy; C. Chen, Chauyi; Y. Fang, Yahsuan; K. Hung, Kaiwei; D. Wu, Dengchyang

Year: 2022

Citations: 10

 

 

Dr. Ruijuan Qu | Environmental Chemistry Award | Best Researcher Award

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Dr. Ruijuan Qu | Environmental Chemistry Award | Best Researcher Award

Dr. Ruijuan Qu , Nanjing University , China

Ruijuan Qu is an Associate Professor at Nanjing University, China, specializing in environmental chemistry and the transformation of organic pollutants. With a strong academic background and extensive research experience, she focuses on the development of quantitative structure-activity relationship (QSAR) models to analyze organic pollutants and improve green degradation methods. Since receiving her Ph.D. from Nanjing University in 2015, she has advanced through various research positions, including assistant researcher and associate researcher, before her current role. She collaborates with international researchers to innovate in environmental technology, notably with Professor Virender K. Sharma at Texas A&M University. Recognized globally, she was listed among Stanford University’s World’s Top 2% Scientists in 2023, emphasizing her significant impact in environmental research.

Professional Profile:

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Summary of Suitability for Award:

Dr. Ruijuan Qu is an exemplary candidate for the Best Researcher Award due to her extensive contributions to environmental science, her innovative research methodologies, and her global recognition. Her work addresses crucial environmental challenges, with real-world applications in water treatment and pollutant degradation. The combination of high-impact publications, patents, collaborations with top global scientists, and her leadership in editorial roles makes her highly deserving of this prestigious recognition. Her commitment to advancing both scientific knowledge and practical environmental solutions places her at the forefront of research in her field.

🎓Education:

Ruijuan Qu completed her undergraduate and postgraduate studies at Nanjing University. After earning her Bachelor’s degree in Environmental Chemistry, she pursued a Ph.D. in Environmental Science, which she completed in 2015. Her doctoral research laid the foundation for her expertise in the environmental transformation of organic pollutants, focusing on quantitative structure-activity relationship (QSAR) analysis. With a commitment to understanding pollutants at a molecular level, she integrated principles of computational chemistry with experimental analysis to map the pathways pollutants take in natural and engineered environments. This innovative approach helped her build a strong knowledge base that informs her teaching and research today. Her education was marked by rigorous training in advanced analytical techniques, preparing her to lead complex projects in environmental science and to contribute valuable insights in her role as an academic and researcher.

🏢Work Experience:

Dr. Ruijuan Qu began her career as an Assistant Researcher at Nanjing University, progressing to Associate Researcher from 2018 to 2019, before being appointed Associate Professor in 2019. She has led several high-impact research projects, primarily focused on the fate of organic pollutants in the environment. Dr. Qu’s work on chemical oxidation processes has uncovered key insights into the catalytic roles of metals in pollution treatment, significantly advancing the field of environmental science. She has also collaborated with global experts, notably Prof. Virender K. Sharma at Texas A&M University, on ferrate oxidation studies, resulting in transformative findings on pollutant degradation mechanisms. Alongside her research, Dr. Qu serves as a managing editor and editorial board member for reputed journals, contributing to the advancement of environmental science literature. Her experience demonstrates her expertise in both independent and collaborative research environments.

🏅Awards:

Ruijuan Qu has earned several prestigious accolades for her research. In 2023, she was named to Stanford University’s esteemed World’s Top 2% Scientists List, recognizing her significant influence and high citation impact in environmental science. Her innovative contributions in environmental chemistry have not only advanced pollution treatment but have also fostered new methodologies in quantitative structure-activity relationship (QSAR) analysis. Dr. Qu’s pioneering work has also been acknowledged through editorial appointments at high-impact journals, such as Reviews of Environmental Contamination and Toxicology and Toxics, where she serves as a managing editor and guest editor. Her reputation in the field is further established by her role as a key collaborator in international research projects, particularly with Texas A&M University. These awards and honors underscore her commitment to impactful, high-quality research and her ongoing contribution to solving complex environmental challenges.

🔬Research Focus:

Dr. Ruijuan Qu’s research focuses on the environmental transformation of organic pollutants, particularly through chemical oxidation processes. Her work employs quantitative structure-activity relationship (QSAR) modeling to analyze pollutant degradation pathways. A major aspect of her research is the catalytic role of various substances, such as bismuth hydroxide, in ferrate oxidation treatment, an innovative approach for water and wastewater purification. Dr. Qu has developed a comprehensive method for pollutant analysis that combines non-target mass spectrometry, preparative separation, and simplified transition state calculations. Her research on the polymerization of phenols during oxidation has revealed critical insights into promoting low-carbon oxidation treatments. Additionally, her studies in silica modification have expanded catalytic activity into the infrared spectrum, enabling more efficient degradation of persistent organic pollutants. This multidisciplinary focus positions Dr. Qu at the forefront of environmental science, advancing sustainable technologies for pollutant management.

Publication Top Notes:

  •  Photodegradation of polychlorinated biphenyls (PCBs) on suspended particles from the Yellow River under sunlight irradiation: QSAR model and mechanism analysis
  •  Effect of Dissolved Organic Matter on the Photodegradation of Decachlorobiphenyl (PCB-209) in Heterogeneous Systems: Experimental Analysis and Excited-State Theory Calculation
  •  Photocatalytic degradation of decabromodiphenyl ethane (DBDPE) by wide solar spectrum-responsive nitrogen doped silica
  • Effect of small-molecule phenolic compounds on the removal of triclosan (TCS) by heat/persulfate process Formation of cross-coupling products and implications for wastewater treatment
  •  Enhanced permanganate oxidation of phenolic pollutants by alumina and potential industrial application