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Assoc. Prof. Dr. Gao Zhenzhen | Heterocycle Synthesis | Green Chemistry Award

Dean at Liaocheng University | China

Dr. Zhenzhen Gao is an Associate Professor at the School of Pharmacy and Food Engineering, Liaocheng University, China. She has been a faculty member at Liaocheng University since 2017, advancing from Lecturer to Associate Professor in 2025. Dr. Gao’s research lies at the intersection of synthetic organic chemistry and medicinal chemistry, with a focus on phosphine-catalyzed reactions and the development of biologically active molecules. She has published in reputable journals such as Molecules and International Journal of Molecular Sciences, contributing significant advancements in the synthesis of maleimide derivatives and their biological applications. She has successfully led a Shandong Provincial Natural Science Foundation General Project on the design and synthesis of α-allenoates with electron-withdrawing groups and novel cyclization reactions. Her work integrates chemical innovation with potential therapeutic value, bridging fundamental organic synthesis with applied pharmaceutical research. Dr. Gao is committed to advancing green, efficient, and biologically relevant synthetic methodologies.

Professional Profile

Orcid

Education 

Dr. Zhenzhen Gao holds advanced academic training in pharmaceutical and chemical sciences, having completed her higher education in China with a specialization in organic chemistry and drug synthesis. She developed a strong foundation in organic reaction mechanisms, catalysis, and structure–activity relationships during her postgraduate studies. Her academic journey emphasized both theoretical and experimental approaches, enabling her to work on designing and synthesizing functionalized organic compounds with potential biological activity. While formal education details are not specified, her expertise and publications reflect extensive training in synthetic methodologies, heterocyclic chemistry, and phosphine-catalyzed transformations. Dr. Gao’s education also involved collaborative research projects, where she gained experience with interdisciplinary teams combining chemistry, pharmacology, and materials science. This academic background has equipped her with the skills to develop innovative molecular scaffolds, optimize reaction conditions, and explore the medicinal potential of novel compounds—forming the basis of her later independent research career at Liaocheng University.

Experience 

Dr. Zhenzhen Gao began her academic career in July 2017 as a Lecturer at the School of Pharmacy and Food Engineering, Liaocheng University, where she contributed to teaching, curriculum development, and guiding undergraduate research. Over the next seven years, she expanded her research portfolio in organic synthesis, focusing on phosphine-catalyzed transformations and the synthesis of biologically relevant molecules. In January 2025, she was promoted to Associate Professor, recognizing her academic contributions and leadership in research. She has successfully led projects funded by the Shandong Provincial Natural Science Foundation, including the design and synthesis of α-allenoates with electron-withdrawing substituents and development of new cyclization methodologies. Dr. Gao’s professional experience combines innovative laboratory research with mentorship, academic service, and scholarly publishing. She collaborates with multidisciplinary teams to bridge chemical synthesis with pharmaceutical applications, contributing to advancements in both fundamental organic chemistry and applied medicinal chemistry.

Awards 

While no specific national or international awards are listed, Dr. Zhenzhen Gao’s professional achievements reflect significant academic recognition. Her promotion to Associate Professor at Liaocheng University in 2025 is a testament to her sustained research productivity, teaching excellence, and contribution to the university’s scientific standing. She has been entrusted with leading a competitive Shandong Provincial Natural Science Foundation General Project—an acknowledgment of her capability to conduct innovative, high-impact research. Her publications in high-quality, peer-reviewed journals such as Molecules and International Journal of Molecular Sciences demonstrate scholarly recognition from the scientific community. These achievements collectively serve as academic milestones, indicating her growing influence in the field of organic synthesis and medicinal chemistry. Through her leadership in funded projects, consistent publication record, and active involvement in academic activities, Dr. Gao has built a professional profile characterized by scientific rigor, innovation, and dedication to advancing chemical research.

Research Interests 

Dr. Zhenzhen Gao’s research interests center on synthetic organic chemistry, with a focus on phosphine-catalyzed reactions and the design of novel biologically active molecules. She specializes in the synthesis of α-allenoates containing electron-withdrawing substituents and the development of innovative cyclization methodologies. Her work explores the creation of functionalized heterocycles and maleimide derivatives, aiming to expand their potential in medicinal chemistry and pharmaceutical development. Dr. Gao is particularly interested in reaction mechanism elucidation, optimizing reaction efficiency, and achieving high selectivity in complex molecule synthesis. She also engages in studying structure–activity relationships (SAR) to understand how chemical modifications influence biological activity. By integrating synthetic strategies with biological evaluation, her research seeks to contribute to the development of new therapeutic agents. Additionally, she is interested in advancing green and sustainable chemistry practices, designing synthetic pathways that minimize environmental impact while maximizing chemical and pharmacological value.

Publication Top Notes

  • Title: Antifungal Activity and Multi-Target Mechanism of Action of Methylaervine on Candida albican
    Year: 2024 (June 24)

  • Title: Synthesis of 3,4-Disubstituted Maleimide Derivatives via Phosphine-Catalyzed Isomerization of α-Succinimide-Substituted Allenoates Cascade γ′-Addition with Aryl Imines
    Year: 2024

  • Title: Phosphine-Catalyzed γ′-Carbon 1,6-Conjugate Addition of α-Succinimide Substituted Allenoates with Para-Quinone Methides: Synthesis of 4-Diarylmethylated 3,4-Disubstituted MaleimidesYear: 2024 (May 31

Conclusion 

In summary, Dr. Zhenzhen Gao is an accomplished organic chemist whose career reflects a balance between innovative research and academic dedication. From her early role as a Lecturer to her promotion as Associate Professor, she has demonstrated consistent growth in scholarship, leadership, and project management. Her research on phosphine-catalyzed transformations and novel heterocyclic compounds bridges the gap between fundamental organic synthesis and potential medicinal applications. The successful execution of a Shandong Provincial Natural Science Foundation project underscores her capacity for impactful, funded research. Through publications in respected international journals, she has contributed valuable knowledge to the fields of synthetic methodology and medicinal chemistry.

 

Gao Zhenzhen | Heterocycle Synthesis | Green Chemistry Award

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