Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Best Researcher Award

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Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Best Researcher Award

Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Ph.D., Master’s Supervisor at Inner Mongolia Medical University, School of Basic Medical Sciences, China 

Dr. Pengwei Zhao is a Professor at the School of Basic Medical Sciences, Inner Mongolia Medical University, he serves as a master’s supervisor and holds various academic positions. He is a member of the Jiusan Society and actively contributes to scientific research as a registered reviewer for Medical Science Monitor and Chinese Journal of Tissue Engineering Research. He is also a youth editorial board member of Modern Oncology and a director of the Inner Mongolia Bioengineering Society. His research focuses on tumor immunology and pharmacological mechanisms of Mongolian medicine. Dr. Zhao has led multiple national and regional research projects, including studies on β-defensins, immune resistance, and cancer treatment mechanisms. His contributions to microbiology and oncology are widely recognized, with several impactful publications in international journals.

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Summary of Suitability for Award:

Dr. Pengwei Zhao, a distinguished Professor at Inner Mongolia Medical University, has made significant contributions to tumor immunology, cancer pharmacology, and Mongolian medicine. His research on β-defensins and their role in immune modulation and cancer therapy has led to groundbreaking findings, particularly in colorectal and triple-negative breast cancer (TNBC). With numerous high-impact publications, including in Pharmacogenomics Journal and World Journal of Gastrointestinal Oncology, his work is recognized globally. His ongoing National Natural Science Foundation of China project further highlights his leadership in cancer research.  Dr. Pengwei Zhao’s extensive research, innovative methodologies, and interdisciplinary approach make him an outstanding candidate for the “Best Researcher Award”. His contributions to immunotherapy, autophagy, and microbiome-related cancer treatments have the potential to shape future oncological therapies. Recognizing him with this award would honor his pioneering discoveries and impact on global cancer research.

🎓Education:

Dr. Pengwei Zhao holds a Ph.D. in Basic Medical Sciences with a specialization in tumor immunology and pharmacology. His doctoral research focused on β-defensin-mediated immune modulation and cancer therapy. He pursued his higher education at Inner Mongolia Medical University, where he developed expertise in molecular biology, pharmacology, and immunology. His early education emphasized microbiology and traditional Mongolian medicine. Dr. Zhao further enhanced his skills through postdoctoral research and collaborations with leading scientists in cancer biology. His education provided a strong foundation in oncological pharmacology, signaling pathways, and immune resistance mechanisms. He has continuously expanded his knowledge through national and international conferences, workshops, and training programs. His academic journey reflects a commitment to translational research, bridging basic science with clinical applications in cancer therapy.

🏢Work Experience:

Dr. Zhao has been a Professor at Inner Mongolia Medical University for several years, where he also serves as a Master’s Supervisor. His professional roles extend beyond teaching, as he holds multiple directorial positions in national and regional scientific societies. He is a reviewer for prestigious journals, including Medical Science Monitor and Chinese Journal of Digestive Diseases. As a youth editorial board member of Modern Oncology, he actively contributes to cancer research. He has successfully led multiple research projects funded by national and regional agencies, focusing on cancer immunology, microbiology, and Mongolian medicine-based therapies. Additionally, Dr. Zhao has conducted collaborative research on β-defensins, autophagy, and immune resistance mechanisms. His expertise in pharmacological pathways and microbial interactions has significantly advanced the understanding of cancer treatment. He has also been invited as a speaker and panelist at various oncology and pharmacology conferences.

🏅Awards: 

Dr. Pengwei Zhao has received multiple prestigious awards and honors in recognition of his contributions to tumor immunology and Mongolian medicine research. He has been honored by the Inner Mongolia Medical University for excellence in research and mentorship. His work on β-defensins and their role in cancer has earned him accolades from Inner Mongolia’s Science and Technology Department. He has also received distinguished reviewer awards from journals such as Medical Science Monitor and Chinese Journal of Tissue Engineering Research. As a key member of the Chinese Society of Ethnomedicine and Pharmacy, he has been acknowledged for his research on the pharmacological mechanisms of traditional Mongolian medicine. His contributions to microbiology and immunology have been recognized by the Inner Mongolia Microbiology Society, and he has been invited as a young committee member of the Chinese Microbiological Society’s Clinical Microbiology Professional Committee.

🔬Research Focus:

Dr. Pengwei Zhao’s research primarily focuses on tumor immunology, cancer pharmacology, and the therapeutic potential of Mongolian medicine. He investigates the molecular mechanisms of β-defensins in cancer, particularly their role in immune regulation and tumor suppression. His work explores how β-defensin-1 peptides modulate PD-1/PD-L1 immune resistance in colorectal cancer. Additionally, he studies Mongolian medicinal formulations like Sendeng-4 and their mechanisms against skin cancer. His research also extends to microbiology, analyzing how bacterial infections, such as those caused by Staphylococcus aureus and Klebsiella pneumoniae, influence lung epithelial immune responses. Dr. Zhao has also contributed significantly to understanding long noncoding RNAs (lncRNAs) and their regulatory impact on autophagy pathways in cancer. His interdisciplinary approach integrates immunology, molecular biology, and ethnopharmacology, providing novel insights into cancer therapy, host-pathogen interactions, and the development of targeted immunotherapies.

Publication Top Notes:

Upregulation of p300 in paclitaxel-resistant TNBC: implications for cell proliferation via the PCK1/AMPK axis

Authors: P. Zhao, Pengwei; J. Cui, Jiaxian; X. Wang, Xiumei

Journal: Pharmacogenomics Journal

Year: 2024

Citations: 2

Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506

Authors: Y. Zhao, Yuxin; Y. Cui, Yan; X. Li, Xinhong; L. Bao, Lili; P. Zhao, Pengwei

Journal: World Journal of Gastrointestinal Oncology

Year: 2024

Citations: 3

Effect of Staphylococcus aureus in pneumonia mouse model on promotion of mBD-3 expression through ERK1/2

Authors: Yongqing Ni, Xiaoduo Bi, Pengwei Zhao

Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice

Authors: Yang W, Li T, An S, Chen R, Zhao Y, Cui J, Zhang M, Lu J, Tian Y, Bao L, Zhao P

Journal: Microbiol Spectrum

Year: 2025

LPS Promoted HPMEC Autophagy by Suppression of the PI3K/Akt/mTOR through Inhibited TIMAP-Promoted Moesin Expression in Sepsis

Authors: Jili Wen, Pengwei Zhao, HuiJuan Ren, JunMin Wu

Journal: Journal of Biological Regulators and Homeostatic Agents

Year: 2023

 

Assoc. Prof. Dr. Ranjan Khunt | Medicinal Chemistry | Best Researcher Award

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Assoc. Prof. Dr. Ranjan Khunt | Medicinal Chemistry | Best Researcher Award

Assoc. Prof. Dr. Ranjan Khunt , Saurashtra University , India

Dr. Ranjan C. Khunt is an accomplished Associate Professor in the Department of Chemistry at Saurashtra University, Rajkot, with over 25 years of teaching and 20 years of research experience. He holds an M.Sc. and Ph.D. from Saurashtra University, specializing in Heterocyclic Medicinal Chemistry, Nano-Science, and Spectroscopy. Dr. Khunt has significantly contributed to nano-science and method development, focusing on advancing spectroscopy and medicinal chemistry. He has published 105 research papers and holds 7 patents. With a track record of guiding 14 research students and mentoring 3 current students, Dr. Khunt is committed to fostering the next generation of chemists. His leadership is further demonstrated by his academic service, including serving as a member of the National Magnetic Resonance Society and receiving recognition for his teaching excellence and research achievements.

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Summary of Suitability for Award:

Dr. Ranjan C. Khunt is highly suitable for the Best Researcher Award due to his remarkable contributions in Medicinal Chemistry, Nano-Science, and Spectroscopy. With over 20 years of research experience, Dr. Khunt has authored 105 research papers and holds 7 patents, underscoring his prolific output and innovation in the field. His focus on developing novel heterocyclic compounds with potential medicinal applications, as well as his expertise in nano-materials for environmental and medical purposes, has had a significant impact on both theoretical and applied chemistry. Moreover, his contributions to spectroscopic methods have advanced chemical analysis techniques. Dr. Khunt’s leadership in guiding 14 research students and his mentorship in a wide array of interdisciplinary projects demonstrate his commitment to fostering future researchers. His numerous awards, including the Best Teacher Award and recognition by institutions like the National Magnetic Resonance Society, further solidify his candidacy for this prestigious honor.

🎓Education:

Dr. Ranjan C. Khunt’s educational journey began at Saurashtra University, where he completed both his M.Sc. and Ph.D. in Chemistry. His doctoral research focused on Heterocyclic Medicinal Chemistry, a field that would shape his subsequent career. Throughout his academic journey, he gained extensive knowledge in Nano-Science and Spectroscopy, which became key areas of his research expertise. Dr. Khunt’s research interests in these fields reflect a strong foundation in both theoretical and practical aspects of chemistry. His academic qualifications provided him with a robust understanding of the intersection between chemistry, medicinal applications, and cutting-edge technological developments. Dr. Khunt’s commitment to his education extended beyond the classroom as he engaged in continuous learning and contributed to the field’s advancement through teaching and research at Saurashtra University, where he remains an influential figure in the academic community.

🏢Work Experience:

Dr. Ranjan C. Khunt has a distinguished teaching and research career spanning over 25 years. He has been an Associate Professor at the Department of Chemistry, Saurashtra University, Rajkot, for more than two decades, where he has mentored numerous students and played a pivotal role in the university’s academic development. His expertise spans Heterocyclic Medicinal Chemistry, Nano-Science, Spectroscopy, and Method Development and Validation. With 20 years of research experience, Dr. Khunt has led groundbreaking work in these fields, contributing to the development of new methods and technologies. In addition to his teaching responsibilities, he has guided 14 research students, fostering a research-driven environment at the university. Dr. Khunt’s academic career is also marked by 17 invitations from other institutions, reflecting his reputation as a leader in his field. His research projects have resulted in valuable advancements, and his work continues to influence the future of chemistry education and research.

🏅Awards: 

Dr. Ranjan C. Khunt’s academic and professional excellence has been recognized through various prestigious awards and honors. He was awarded the Best Teacher Award by the Institute of Scholars, which acknowledged his exceptional teaching abilities and commitment to student development. In addition, he received the Nation Builder’s Award from the Rotary Club of Rajkot Prime, a testament to his contributions to education and society. Dr. Khunt was honored with the Fast Track Young Scientist Fellowship, which highlighted his emerging role in advancing scientific research. He also serves as an Executive Committee Member of the National Magnetic Resonance Society, Bangalore, an esteemed position that reflects his influence in the field of spectroscopy. These recognitions, along with 6 research projects and his impressive publication record, underscore Dr. Khunt’s dedication to the scientific community, educational excellence, and innovation.

🔬Research Focus:

Dr. Ranjan C. Khunt’s research focuses on the intersection of Medicinal Chemistry, Nano-Science, and Spectroscopy, areas in which he has made significant advancements. His expertise in Heterocyclic Chemistry has led to the development of novel compounds with medicinal applications, especially those aimed at improving health outcomes. Dr. Khunt’s work in Nano-Science is driven by the exploration of nanomaterials for use in various chemical processes and their applications in drug delivery systems, diagnostics, and therapeutic interventions. Additionally, his contributions to Spectroscopy and Method Development have been fundamental in advancing analytical techniques, aiding in precise measurement and characterization of chemical compounds. His research aims to bridge the gap between fundamental chemical knowledge and practical applications in medicine, pharmaceuticals, and environmental chemistry. Dr. Khunt’s work is critical for advancing both the theoretical and practical aspects of modern chemistry, especially in sustainable and health-related areas.

Publication Top Notes:

Synthesis, antitubercular evaluation and 3D-QSAR study of N-phenyl-3-(4-fluorophenyl)-4-substituted pyrazole derivatives
Authors: RC Khunt, VM Khedkar, RS Chawda, NA Chauhan, AR Parikh, …
Journal: Bioorganic & Medicinal Chemistry Letters
Citations: 109
Year: 2012

Synthesis of some new heterocyclic compounds with potential biological activity
Authors: DP Bhoot, RC Khunt, VK Shankhavara, HH Parekh
Journal: Journal of Sciences, Islamic Republic of Iran
Citations: 36
Year: 2006

Plant pigments as dietary anticancer agents
Author: RK Upadhyay
Journal: International Journal of Green Pharmacy (IJGP)
Citations: 33
Year: 2018

Synthesis of certain 1, 3, 4-oxadiazoles as potential antitubercular and antimicrobial agents
Authors: SR Dhol, AS Bhimani, RC Khunt, AR Parikh
Journal: Indian Journal of Heterocyclic Chemistry
Citations: 25
Year: 2005

Synthesis and biological evaluation of cyanopyridine and isozazole derivatives
Authors: RC Khunt, NJ Datta, FM Bharmal, GP Mankad, AR Parikh
Journal: Indian Journal of Heterocyclic Chemistry
Citations: 24
Year: 2000

Discovery of hybrid purine-quinoline molecules and their cytotoxic evaluation
Authors: KM Kapadiya, RC Khunt
Journal: Letters in Drug Design & Discovery
Citations: 23
Year: 2019

Synthesis of Purine‐based Triazoles by Copper (I)‐catalyzed Huisgen Azide–Alkyne Cycloaddition Reaction
Authors: K Kapadiya, Y Jadeja, R Khunt
Journal: Journal of Heterocyclic Chemistry
Citations: 23
Year: 2018

Synthesis of some new 4-thiazolidinones as biologically potent agents
Authors: NJ Datta, RC Khunt, AR Parikh
Journal: NISCAIR-CSIR, India
Citations: 23
Year: 2002

Dihedral angle study in Hesperidin using NMR Spectroscopy
Authors: YS Jadeja, KM Kapadiya, HJ Jebaliya, AK Shah, RC Khunt
Journal: Magnetic Resonance in Chemistry
Citations: 21
Year: 2017

UV-Vis spectrophotometric assay determination of oral antiplatelet ticagrelor drug in pharmaceutical formulation: Application to content uniformity
Authors: D Pandya, M Patel, R Ghediya, A Shah, R Khunt
Journal: Journal of Chemical and Pharmaceutical Research
Citations: 20
Year: 2016

 

 

 

 

 

Prof. Dr. Shivaji Thore | Medicinal Chemistry Award | Best Researcher Award

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Prof. Dr. Shivaji Thore | Medicinal Chemistry Award | Best Researcher Award

Prof. Dr. Shivaji Thore , Vinayakrao Patil Mahavidyalaya , India

Dr. Shivaji Nivrutti Thore serves as the Principal at M.S.P. Mandal’s Vinayakrao Patil Mahavidyalaya in Vaijapur, Aurangabad District. With an academic journey that began with a passion for Chemistry, he has built a remarkable career in education and research. Dr. Thore completed his Ph.D. in Chemistry from Dr. Babasaheb Ambedkar Marathwada University (BAMU), Aurangabad, has held esteemed positions, including Principal and Chairman of the Board of Studies in Chemistry at BAMU. He has over 32 years of teaching experience, 18 of which are in administrative roles. Dr. Thore is an accomplished researcher with 62 publications, an h-index of 16, and numerous books, patents, and awards to his credit, including international recognitions. His expertise spans across organic chemistry, educational administration, and quality assurance, making him a highly regarded leader in both academic and scientific circles.

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Summary of Suitability for Award:

Shivaji Nivrutti Thore demonstrates a substantial track record of research, leadership, and academic contributions that would make him a competitive candidate for the “Best Researcher Award.” As the Principal of M.S.P. Mandal’s Vinayakrao Patil Mahavidyalaya and with over 32 years of experience in teaching and administration, he brings extensive expertise in both research and institutional leadership. His academic qualifications, including a Ph.D. in Chemistry and a strong publication record with 62 research papers, underscore his depth in the field of chemistry, especially organic chemistry. He has guided 12 Ph.D. students, showing a commitment to mentoring the next generation of researchers.

🎓Education:

Dr. Shivaji Nivrutti Thore’s educational journey is grounded in his passion for the sciences, beginning with his secondary education from S.S.C. Board, Aurangabad. He pursued higher secondary studies in science at M.S.P. Mandal’s Vinayakrao Patil Mahavidyalaya, Vaijapur, and completed his HSC. He then embarked on a B.Sc. in Chemistry, Botany, and Zoology, securing first division honors from Dr. Babasaheb Ambedkar Marathwada University,  in Aurangabad. Driven by a keen interest in Organic Chemistry, he completed his M.Sc, graduating with a gold medal. Dr. Thore’s academic journey culminated in a Ph.D. in Chemistry , reflecting his deep commitment to advancing knowledge in the field. His educational foundation has paved the way for a distinguished career in academia and research.

🏢Work Experience:

Dr. Thore has over 32 years of experience in academia, beginning as a Lecturer in Chemistry , at M.S.P. Mandal’s Vinayakrao Patil Mahavidyalaya, Vaijapur. He advanced to Senior Scale Lecturer and Reader, accumulating valuable teaching and research experience. , he became Principal in the Professor Grade, and since then, he has led institutions, including Deogiri College, Aurangabad, with a total of 18 years in administrative positions. Dr. Thore’s extensive experience includes significant roles at BAMU, such as Chairman of the Board of Studies in Chemistry and Member of the Academic Council and Senate. His contributions also encompass quality assurance and accreditation processes, solidifying his reputation as a leader in institutional development and academic excellence.

🏅Awards:

Dr. Shivaji Thore has earned several prestigious awards throughout his career. In 1990, he was awarded the Gold Medal at the M.Sc. level by Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. The Indian Council of Chemists recognized him as a Young Scientist in 2001, underscoring his early contributions to the field. His international acclaim includes recognition as one of the “2000 Outstanding Intellectuals of the 21st Century” by the International Biographical Center (IBC) in London , and he was subsequently named among the “Top 100 Scientists” by the same institution Dr. Shivaji Thore is also a Fellow of the International Congress of Chemistry and Environment, the American Chemical Society, and the Indian Chemical Society, acknowledging his enduring impact on the chemical sciences.

🔬Research Focus:

Dr. Shivaji Thore’s research is centered on organic chemistry, with a particular emphasis on heterocyclic compounds, medicinal chemistry, and green chemistry. His work explores efficient methodologies in synthetic organic chemistry, including catalysis and environmentally benign processes. He has contributed significantly to developing innovative compounds with potential applications in pharmaceuticals and industrial chemistry. His extensive publication record, comprising 62 articles in peer-reviewed journals, highlights his focus on sustainable chemical processes and novel synthetic techniques. Dr. Thore has also supervised multiple Ph.D. students, furthering research in these areas. His commitment to advancing knowledge is reflected in his impressive i-10 index of 25 and h-index of 16, demonstrating the impact and reach of his scientific work.

Publication Top Notes:

  •  Synthesis and anti-inflammatory activity of some new 4,5-dihydro-1,5-diaryl-1H-pyrazole-3-substituted-heteroazole derivatives
    • Citations: 71
  • Sodium 2-(2-pyridin-3-ylethylamino) sulfonate: an efficient ligand and base for palladium-catalyzed Heck reaction in aqueous media
    • Citations: 46
  • Glyoxylic acid as catalyst: A simple selective synthesis of 1,2-disubstituted benzimidazoles in aqueous media
    • Citations: 45
  • Biological role of chalcones in medicinal chemistry
    • Citations: 42
  •  Sodium 2-(2-pyridin-3-ylethylamino) ethyl sulfonate: an efficient ligand and base for palladium-catalyzed Suzuki reaction in aqueous media
    • Citations: 37

 

 

 

 

Prof. Ahmed elhenawy | Medicinal Chemistry |Best Researcher Award

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Prof. Ahmed elhenawy | Medicinal Chemistry | Best Researcher Award

Prof. Ahmed elhenawy, Azhar unveristy, Egypt

Prof. Ahmed Abd El-Emonam El-Said El-Henawy is a distinguished Egyptian chemist, born on December 23, 1978, in Hellwan, Egypt. With an h-index of 22 and 126 publications, he is a prominent figure in organic chemistry, particularly in peptide synthesis and drug development. Currently, he serves as an Assistant Professor at Albaha University, KSA, and as a Professor at Al-Azhar University, Egypt. With extensive teaching experience, he has guided numerous undergraduate and postgraduate students in organic chemistry. His contributions to research and academia reflect a commitment to advancing knowledge in chemical sciences, emphasizing innovative approaches to synthesizing biologically active compounds.

Professional Profile:

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Summary of Suitability for Award:

Prof. Ahmed Abd El-Emonam El-Said El-Henawy is an exemplary candidate for the “Best Researcher Awards,” primarily due to his substantial contributions to the field of organic chemistry and his commitment to advancing scientific knowledge. With an h-index of 22 and 126 publications, his research output demonstrates a high level of impact and relevance within the academic community. His specialization in peptide synthesis, particularly the development of novel amino acid derivatives with potential antimicrobial and anticancer activities, showcases his innovative approach to addressing critical health challenges.

🎓Education:

Prof. El-Henawy completed his Bachelor’s degree in Special Chemistry at Al-Azhar University in 2000. He pursued a Master’s degree in Organic Chemistry, focusing on amino acids and proteins, graduating in 2005. His doctoral research, completed in 2008, investigated new amino acid derivatives with expected biological activities. He has held various academic positions at Al-Azhar University, including Demonstrator, Assistant Lecturer, Lecturer, Associate Professor, and Professor, contributing to the department’s growth and the education of future chemists. Additionally, he has been involved in teaching at Albaha University since 2012, where he continues to inspire students through comprehensive organic chemistry courses.

🏢Work Experience:

Prof. El-Henawy has over two decades of experience in academia and research. He began his career as a Demonstrator at Al-Azhar University in 2002 and progressed to the role of Assistant Lecturer in 2005. He became a Lecturer in 2008, then an Associate Professor in 2014, and is currently a Professor. His research focuses on the synthesis of dipeptides and related compounds with potential antimicrobial and anticancer activities. He has developed expertise in various laboratory techniques, including multistep synthesis, chromatographic purification, and spectroscopic analysis. Prof. El-Henawy has supervised numerous M.Sc. and Ph.D. theses in peptide synthesis, reflecting his dedication to nurturing the next generation of chemists. His collaborative research has been presented at international conferences and published in reputable journals.

🏅Awards:

Prof. El-Henawy has received recognition for his contributions to the field of chemistry and education. His research has led to significant advancements in organic chemistry, particularly in synthesizing biologically active compounds. While specific awards are not listed, his h-index of 22 and 126 publications highlight his impact and credibility within the scientific community. His involvement in international conferences showcases his commitment to sharing knowledge and fostering collaboration among researchers. By mentoring students and guiding their research endeavors, he has played a vital role in shaping future chemists. Prof. El-Henawy’s dedication to teaching and research has earned him respect among colleagues and students alike, establishing him as a key figure in the chemistry department at both Al-Azhar University and Albaha University

🔬Research Focus:

Prof. El-Henawy’s research primarily focuses on organic chemistry, emphasizing peptide synthesis and the development of novel amino acid derivatives. His work includes synthesizing dipeptides, tri-, tetra-, and pentapeptides with antimicrobial properties. He has also explored new sulfonamide derivatives as potential antimicrobial agents and synthesized 2-amino-1,3,4-thiadiazole derivatives with anticancer potential. His research incorporates advanced laboratory techniques, such as multistep synthesis and chromatographic isolation. Prof. El-Henawy utilizes various spectroscopic methods to elucidate the structures of synthesized compounds, contributing to the understanding of their biological activities. His commitment to pharmacological research is evident in projects funded by Albaha University, focusing on the pharmacokinetics and toxicodynamics of pharmaceutical compounds. Through his innovative research, Prof. El-Henawy aims to discover new therapeutic agents that address critical health challenges.

Publication Top Notes:

  • Title: Exploring the anti-diabetic activity of benzimidazole containing Schiff base derivatives: In vitro α-amylase, α-glucosidase inhibitions and in silico studies
  • Title: Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking, dynamics, MM-GBSA …
  • Title: Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
  • Title: Flurbiprofen clubbed schiff’s base derivatives as potent anticancer agents: In Vitro and In Silico approach towards breast cancer
  • Title: Synthesis, anticancer, α-glucosidase inhibition, molecular docking and dynamics studies of hydrazone-Schiff bases bearing polyhydroquinoline scaffold: In vitro and in silico