Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Best Researcher Award

Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Best Researcher Award

Prof. Dr. Pengwei Zhao | Medicinal Chemistry | Ph.D., Master’s Supervisor at Inner Mongolia Medical University, School of Basic Medical Sciences, China 

Dr. Pengwei Zhao is a Professor at the School of Basic Medical Sciences, Inner Mongolia Medical University, he serves as a master’s supervisor and holds various academic positions. He is a member of the Jiusan Society and actively contributes to scientific research as a registered reviewer for Medical Science Monitor and Chinese Journal of Tissue Engineering Research. He is also a youth editorial board member of Modern Oncology and a director of the Inner Mongolia Bioengineering Society. His research focuses on tumor immunology and pharmacological mechanisms of Mongolian medicine. Dr. Zhao has led multiple national and regional research projects, including studies on β-defensins, immune resistance, and cancer treatment mechanisms. His contributions to microbiology and oncology are widely recognized, with several impactful publications in international journals.

Professional Profile : 

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Summary of Suitability for Award:

Dr. Pengwei Zhao, a distinguished Professor at Inner Mongolia Medical University, has made significant contributions to tumor immunology, cancer pharmacology, and Mongolian medicine. His research on β-defensins and their role in immune modulation and cancer therapy has led to groundbreaking findings, particularly in colorectal and triple-negative breast cancer (TNBC). With numerous high-impact publications, including in Pharmacogenomics Journal and World Journal of Gastrointestinal Oncology, his work is recognized globally. His ongoing National Natural Science Foundation of China project further highlights his leadership in cancer research.  Dr. Pengwei Zhao’s extensive research, innovative methodologies, and interdisciplinary approach make him an outstanding candidate for the “Best Researcher Award”. His contributions to immunotherapy, autophagy, and microbiome-related cancer treatments have the potential to shape future oncological therapies. Recognizing him with this award would honor his pioneering discoveries and impact on global cancer research.

🎓Education:

Dr. Pengwei Zhao holds a Ph.D. in Basic Medical Sciences with a specialization in tumor immunology and pharmacology. His doctoral research focused on β-defensin-mediated immune modulation and cancer therapy. He pursued his higher education at Inner Mongolia Medical University, where he developed expertise in molecular biology, pharmacology, and immunology. His early education emphasized microbiology and traditional Mongolian medicine. Dr. Zhao further enhanced his skills through postdoctoral research and collaborations with leading scientists in cancer biology. His education provided a strong foundation in oncological pharmacology, signaling pathways, and immune resistance mechanisms. He has continuously expanded his knowledge through national and international conferences, workshops, and training programs. His academic journey reflects a commitment to translational research, bridging basic science with clinical applications in cancer therapy.

🏢Work Experience:

Dr. Zhao has been a Professor at Inner Mongolia Medical University for several years, where he also serves as a Master’s Supervisor. His professional roles extend beyond teaching, as he holds multiple directorial positions in national and regional scientific societies. He is a reviewer for prestigious journals, including Medical Science Monitor and Chinese Journal of Digestive Diseases. As a youth editorial board member of Modern Oncology, he actively contributes to cancer research. He has successfully led multiple research projects funded by national and regional agencies, focusing on cancer immunology, microbiology, and Mongolian medicine-based therapies. Additionally, Dr. Zhao has conducted collaborative research on β-defensins, autophagy, and immune resistance mechanisms. His expertise in pharmacological pathways and microbial interactions has significantly advanced the understanding of cancer treatment. He has also been invited as a speaker and panelist at various oncology and pharmacology conferences.

🏅Awards: 

Dr. Pengwei Zhao has received multiple prestigious awards and honors in recognition of his contributions to tumor immunology and Mongolian medicine research. He has been honored by the Inner Mongolia Medical University for excellence in research and mentorship. His work on β-defensins and their role in cancer has earned him accolades from Inner Mongolia’s Science and Technology Department. He has also received distinguished reviewer awards from journals such as Medical Science Monitor and Chinese Journal of Tissue Engineering Research. As a key member of the Chinese Society of Ethnomedicine and Pharmacy, he has been acknowledged for his research on the pharmacological mechanisms of traditional Mongolian medicine. His contributions to microbiology and immunology have been recognized by the Inner Mongolia Microbiology Society, and he has been invited as a young committee member of the Chinese Microbiological Society’s Clinical Microbiology Professional Committee.

🔬Research Focus:

Dr. Pengwei Zhao’s research primarily focuses on tumor immunology, cancer pharmacology, and the therapeutic potential of Mongolian medicine. He investigates the molecular mechanisms of β-defensins in cancer, particularly their role in immune regulation and tumor suppression. His work explores how β-defensin-1 peptides modulate PD-1/PD-L1 immune resistance in colorectal cancer. Additionally, he studies Mongolian medicinal formulations like Sendeng-4 and their mechanisms against skin cancer. His research also extends to microbiology, analyzing how bacterial infections, such as those caused by Staphylococcus aureus and Klebsiella pneumoniae, influence lung epithelial immune responses. Dr. Zhao has also contributed significantly to understanding long noncoding RNAs (lncRNAs) and their regulatory impact on autophagy pathways in cancer. His interdisciplinary approach integrates immunology, molecular biology, and ethnopharmacology, providing novel insights into cancer therapy, host-pathogen interactions, and the development of targeted immunotherapies.

Publication Top Notes:

Upregulation of p300 in paclitaxel-resistant TNBC: implications for cell proliferation via the PCK1/AMPK axis

Authors: P. Zhao, Pengwei; J. Cui, Jiaxian; X. Wang, Xiumei

Journal: Pharmacogenomics Journal

Year: 2024

Citations: 2

Human β-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long non-coding RNA TCONS_00014506

Authors: Y. Zhao, Yuxin; Y. Cui, Yan; X. Li, Xinhong; L. Bao, Lili; P. Zhao, Pengwei

Journal: World Journal of Gastrointestinal Oncology

Year: 2024

Citations: 3

Effect of Staphylococcus aureus in pneumonia mouse model on promotion of mBD-3 expression through ERK1/2

Authors: Yongqing Ni, Xiaoduo Bi, Pengwei Zhao

Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice

Authors: Yang W, Li T, An S, Chen R, Zhao Y, Cui J, Zhang M, Lu J, Tian Y, Bao L, Zhao P

Journal: Microbiol Spectrum

Year: 2025

LPS Promoted HPMEC Autophagy by Suppression of the PI3K/Akt/mTOR through Inhibited TIMAP-Promoted Moesin Expression in Sepsis

Authors: Jili Wen, Pengwei Zhao, HuiJuan Ren, JunMin Wu

Journal: Journal of Biological Regulators and Homeostatic Agents

Year: 2023

 

Dr. Jean Moto Ongagna | Theoretical Chemistry | Catalysis Award

Dr. Jean Moto Ongagna | Theoretical Chemistry | Catalysis Award

Dr. Jean Moto Ongagna | Theoretical Chemistry | Lecturer – University of Douala-Cameroon , Cameroon

Dr. Jean Moto Ongagna is a Cameroonian researcher specializing in Theoretical chemistry and Computational Chemistry . He obtained his Ph.D. from the University of Douala in 2021. His expertise spans Density Functional Theory (DFT), Pharmacokinetics (ADMET), Molecular Docking, Molecular Dynamics (MD), and ab initio Molecular Dynamics (ADMP). Dr. Ongagna has contributed significantly to computational chemistry, particularly in studying metal complexes, chemical bonding, and reaction mechanisms. He has participated in prestigious international conferences and workshops, presenting groundbreaking research on chemical bonding interactions. With numerous publications in high-impact journals such as RSC Advances and the International Journal of Quantum Chemistry, his work advances the understanding of transition metal complexes and their applications. He actively collaborates with researchers worldwide and is dedicated to developing computational tools for chemical and biological systems.

Professional Profile : 

Orcid  

Summary of Suitability for Award:

Dr. Jean Moto Ongagna is an outstanding candidate for the “Catalysis Awards”, given his significant contributions to computational catalysis and theoretical chemistry. His research extensively applies Density Functional Theory (DFT), Quantum Chemical Calculations, and Molecular Dynamics (MD) to investigate transition metal complexes, non-standard chemical bonding, and catalytic reaction mechanisms. His studies provide deep insights into metal-ligand interactions, catalytic efficiency, and reaction pathways, which are fundamental for designing novel catalytic systems. Dr. Jean Moto Ongagna’s research in computational catalysis, transition metal chemistry, and theoretical modeling aligns perfectly with the objectives of the “Catalysis Awards”. His work advances the understanding of catalyst behavior, reaction mechanisms, and molecular interactions, making a substantial impact on modern catalysis research. His ability to integrate quantum chemistry tools with catalytic design positions him as a highly suitable candidate for this prestigious recognition.

🎓Education:

Dr. Jean Moto Ongagna pursued his higher education at the University of Douala, Cameroon. He earned a Ph.D. in Theoretical and Computational Chemistry (2021), focusing on Density Functional Theory (DFT) and molecular simulations. In 2016, he completed his Master’s degree in the same field, where he explored the computational analysis of metal-ligand interactions. His Bachelor’s degree in Physical Chemistry (2013) laid the foundation for his research on quantum chemistry and molecular modeling. Before university, he completed his GCE Advanced Level (Baccalauréat D) in 2008 at Laic Private College “La Liberté” in Douala. His education equipped him with expertise in quantum chemistry, molecular docking, and theoretical modeling, enabling him to contribute to cutting-edge research. Throughout his academic journey, he attended specialized workshops and conferences to enhance his skills in computational chemistry, continuously refining his expertise in quantum simulations and advanced chemical theories.

🏢Work Experience:

Dr. Jean Moto Ongagna has extensive experience in Theoretical chemistry and Computational Chemistry, with expertise in Density Functional Theory (DFT), Molecular Docking, Pharmacokinetics (ADMET), and ab initio Molecular Dynamics (ADMP). He has actively participated in international conferences, presenting research on transition metal complexes, chemical bonding, and molecular interactions. He has contributed to significant projects involving the computational study of catalysts, biomolecular interactions, and pharmaceutical compounds. Dr. Ongagna has also collaborated with renowned institutions and researchers worldwide, publishing extensively in high-impact journals. His research experience includes developing and applying quantum chemical tools for investigating metal-ligand interactions and reaction mechanisms. He has been involved in multiple computational chemistry workshops, enhancing his knowledge of secondary metabolite discovery, quantum topology, and electronic structure theory. His contributions have led to a deeper understanding of non-standard chemical bonding and have implications for catalysis, drug design, and materials science.

🏅Awards: 

Dr. Jean Moto Ongagna has received multiple recognitions for his contributions to Theoretical and Computational Chemistry. He has been invited as a speaker at international conferences, including the 4th Commonwealth Chemistry Posters (2023) and the Virtual Conference on Chemistry and Its Applications (2021, 2022). His research on transition metal complexes and quantum chemistry has been published in high-impact journals such as RSC Advances and the International Journal of Quantum Chemistry. He has received accolades for his computational investigations on catalytic and biomolecular systems, contributing to the advancement of quantum chemical methodologies. His participation in scientific workshops at the University of Buea (Cameroon) and Technische Universität Dresden (Germany) further highlights his academic excellence. His continuous engagement in international scientific discussions and collaborations has strengthened his reputation as a leading researcher in quantum chemistry and molecular modeling.

🔬Research Focus:

Dr. Jean Moto Ongagna’s research focuses on Theoretical and Computational Chemistry, particularly Density Functional Theory (DFT), Quantum Chemical Calculations, Molecular Docking, Pharmacokinetics (ADMET), and Molecular Dynamics (MD). He specializes in studying transition metal complexes, non-standard chemical bonds, and catalytic reactions. His work involves topological analysis of chemical interactions using advanced computational techniques such as Quantum Theory of Atoms in Molecules (QTAIM), Energy Decomposition Analysis (EDA), and Natural Bond Orbital (NBO) analysis. He has made significant contributions to understanding palladium complexes, Diels–Alder reactions, and bioactive compounds. His research extends to computational drug discovery, antimicrobial compounds, and bioinorganic chemistry, aiming to bridge the gap between theoretical modeling and experimental applications. By integrating quantum chemical methods with molecular simulations, his studies provide valuable insights into reaction mechanisms, electronic structures, and potential applications in pharmaceuticals, catalysis, and material science.

Publication Top Notes:

Deciphering the Influence of Alkylene Bridged and Chelating Mode on Pd—C and Pd—X (X = Cl, Br, and I) Bonding Interaction Within Bis‐(NHC)‐Palladium Complexes Using Quantum Chemistry Tools

Authors: Gaël Mouzong D’Ambassa, Jean Moto Ongagna, Adjieufack Abel Idrice, Désiré Bikele Mama

Year: 2024

Computational Exploration of the Impact of Low‐Spin and High‐Spin Ground State on the Chelating Ability of Dimethylglyoxime Ligand on Dihalo Transition Metal: A QTAIM, EDA, and CDA Analysis

Authors: Daniel Lissouck, Suzane Leonie Djendo Mazia, Gaël Mouzong D’Ambassa, Jean Moto Ongagna

Year: 2024

Deciphering the Influence of PdII and PdIV Oxidation States on Non-Standard Chemical Bonds Within Bis(N-Heterocyclic Carbene) Complexes: Insights from DFT

Authors: Gaël Mouzong D’Ambassa, Jean Moto Ongagna, Adjieufack Abel Idrice, Désiré Bikele Mama

Year: 2024

Exploring the Mechanism of the Intramolecular Diels–Alder Reaction of (2E,4Z,6Z)-2(allyloxy)cycloocta-2,4,6-trien-1-one Using Bonding Evolution Theory

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2023

In Vitro and In Silico Studies of Antibacterial Activities of Secofriedelane Derivatives from Senna alata (L) Roxb

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2023

How a Chromium Tricarbonyl Complex Catalyzes the [3 + 2] Cycloaddition Reaction of N-Substituted Phenylnitrones with Styrene: A Molecular Electron Density Theory Analysis

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2023

Insight into the Antioxidant and Antiradical Properties of Colorotane Sesquiterpenes Extracted from Warburgia ugandensis: Theoretical Evaluation

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2021

Topological Unraveling of the [3+2] Cycloaddition (32CA) Reaction Between N-Methylphenylnitrone and Styrene Catalyzed by the Chromium Tricarbonyl Complex Using Electron Localization Function and Catastrophe Theory

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2021

B3LYP, M06 and B3PW91 DFT Assignment of nd8 Metal-Bis-(N-Heterocyclic Carbene) Complexes

Authors: Jean Moto Ongagna, Gaël Mouzong D’Ambassa

Year: 2020