Qi Zhang is a Professor at Fudan University, specializing in natural product biosynthesis, mechanistic enzymology, and antibiotic chemical biology. With a strong academic background and significant contributions to his field, he has gained international recognition for his innovative research on RiPP natural products.
Author Metrics
Scopus Profile
Qi Zhang has an impressive citation index of 4700, reflecting the impact and relevance of his work in the scientific community. He has authored nearly 100 papers in high-impact journals, showcasing his prolific contributions to chemistry and biology.
Education
Qi Zhang completed his B.S. in Chemistry at Fudan University before pursuing a PhD in Inorganic Chemistry at the Shanghai Institute of Organic Chemistry under the mentorship of Prof. Wen Liu. He further enhanced his expertise through postdoctoral studies with Prof. Wilfred van der Donk at the University of Illinois at Urbana-Champaign.
Research Focus
Dr. Zhang’s research centers on the biosynthesis of natural products, particularly ribosomally synthesized and post-translationally modified peptides (RiPPs). He investigates enzyme-catalyzed mechanisms and integrates chemical-enzyme processes with continuous flow synthesis, contributing to advancements in synthetic biology and drug discovery.
Professional Journey
After completing his postdoctoral studies, Qi Zhang began his independent research career in 2014 at Fudan University. He rapidly established himself in the academic community, culminating in his promotion to full professor in 2020. His journey reflects a commitment to advancing the fields of chemistry and biology through innovative research.
Honors & Awards
Dr. Zhang’s contributions have been recognized with several prestigious awards, including the ICB Young Chemical Biologist Award and the ACS Chemistry Structure Award. These accolades highlight his significant impact on the scientific community and his leadership in research.
Publications Noted & Contributions
Qi Zhang has published nearly 100 papers in renowned journals such as Nature Chemistry, PNAS, and JACS. His research on RiPP natural products has garnered attention, with findings highlighted in Science and Chemical & Engineering News, showcasing the broad implications of his work in natural product chemistry and drug discovery.
Title: Single-cell transcriptomic analysis reveals the landscape of epithelial-mesenchymal transition molecular heterogeneity in esophageal squamous cell carcinoma
Authors: Guo, D., Sheng, K., Zhang, Q., Yu, J., Zhang, J.
Journal: Cancer Letters
Year: 2024
Volume: 587
Article Number: 216723
Citations: 0
Type: Review • Open Access
Summary: This study utilizes single-cell transcriptomic analysis to explore the molecular heterogeneity associated with epithelial-mesenchymal transition (EMT) in esophageal squamous cell carcinoma. The findings provide insights into the complexities of cancer progression and potential therapeutic targets.
Title: Hi-C, a chromatin 3D structure technique advancing the functional genomics of immune cells
Authors: Liu, R., Xu, R., Yan, S., Li, X., Guo, D.
Journal: Frontiers in Genetics
Year: 2024
Volume: 15
Article Number: 1377238
Citations: 1
Summary: This article discusses the Hi-C technique, which captures the 3D structure of chromatin and its implications for understanding the functional genomics of immune cells. The authors highlight how this method enhances our knowledge of genomic architecture and gene regulation in immunology.
Research Timeline
Since beginning his independent research career in 2014, Dr. Zhang has actively engaged in multiple research projects, completing 10 and currently leading several ongoing initiatives. His research timeline demonstrates a consistent trajectory of innovation and contribution to the field.
Collaborations and Projects
Qi Zhang collaborates with prominent researchers, including Prof. Yvain from the University Grenoble Alpes and Prof. Brandon Morinaka from the National University of Singapore. These collaborations enhance his research capabilities and facilitate knowledge exchange across institutions, leading to impactful projects in chemical biology.
Conclusion
Professor Qi Zhang exemplifies excellence in biochemistry through his innovative research, impressive publication record, and significant recognition in the scientific community. His focus on RiPPs positions him at the forefront of natural product biosynthesis, contributing to advancements in drug discovery and synthetic biology. While his achievements are commendable, embracing broader impacts, interdisciplinary collaboration, and public engagement can further enhance his contributions and legacy in the field. As he continues to lead in research and education, Dr. Zhang’s work holds great promise for the future of biochemistry and its applications.