Dr. Batoul Rostom | Medicinal Chemistry Award | Best Researcher Award

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Dr. Batoul Rostom | Medicinal Chemistry Award | Best Researcher Award

Dr. Batoul Rostom , INSERM-CRM , France

🎓 Dr. Batoul Rostom is a dedicated researcher in medicinal chemistry, currently a postdoctoral fellow at INSERM-Centre de Recherche en Myologie, Sorbonne University. She earned her Ph.D. in Medicinal Chemistry and Cancer Biology, where she focused on synthesizing novel cyclocoumarol derivatives with dual COX-2 inhibitory and anticancer properties. Dr. Rostom has a solid academic foundation in biochemistry and reproductive biology, with experience spanning bioinformatics, synthetic chemistry, and immunology. Her research addresses pressing issues in cancer therapeutics and autoimmune diseases. She has authored impactful publications, contributed to scientific conferences, and mentored students. Dr. Rostom’s work combines innovation with clinical relevance, aiming to bridge the gap between bench research and therapeutic applications.

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Summary of Suitability for Award:

Dr. Batoul Rostom’s remarkable achievements, interdisciplinary expertise, and impactful research make her a deserving candidate for the “Best Researcher Award.” Her ability to translate complex scientific concepts into therapeutic applications reflects her commitment to advancing both knowledge and societal well-being. Dr. Batoul Rostom exemplifies the qualities of an outstanding researcher, with her innovative contributions to medicinal chemistry and cancer biology. Her groundbreaking work in synthesizing cyclocoumarol derivatives as dual COX-2 inhibitors with anticancer properties showcases her ability to address pressing global health challenges.  Dr. Rostom’s impressive academic journey, from her Ph.D. at HESAM University to her postdoctoral role at Sorbonne University, highlights her dedication to advancing science.

🎓Education:

Dr. Batoul Rostom has a strong academic foundation in medicinal chemistry, biochemistry, and reproductive biology. She earned her Ph.D. in Medicinal Chemistry and Cancer Biology from HESAM University in France, where she focused on synthesizing novel cyclocoumarol derivatives with dual COX-2 inhibitory and anticancer properties. Her master’s degree in Reproductive Biology and Medical Aids from Lebanese University  centered on the impact of smoking on TET gene expression in sperm cells, optimizing RNA extraction techniques. She holds a bachelor’s degree in General Biochemistry from Lebanese University, with comprehensive training in molecular biology and biochemistry. Her education integrates interdisciplinary skills, blending synthetic chemistry, molecular biology, and bioinformatics.

🏢Work Experience:

Dr. Batoul Rostom’s career spans diverse research roles. As a postdoctoral researcher at INSERM-Centre de Recherche en Myologie, Sorbonne University , she develops therapeutic strategies for autoimmune myositis and cancer. During her Ph.D. research at CNAM in France, she synthesized and tested innovative cyclocoumarol derivatives targeting COX-2 and cancer pathways.  She led a COVID-19 PCR diagnostic team at Al Hadi Clinic, Lebanon, managing high-pressure operations during the pandemic. She has served as a private tutor , mentoring students in molecular biology and biochemistry. Her master’s internship explored smoking’s effects on male fertility, showcasing her diverse expertise.

🏅Awards:

Dr. Rostom’s remarkable achievements have earned her significant recognition in the field of medicinal chemistry. She was nominated for the prestigious International Chemistry Scientist Award for her groundbreaking contributions. As an active member of the SociĂ©tĂ© de Chimie ThĂ©rapeutique (SCT), her work in therapeutic compound design has been highly acknowledged. Her Ph.D. journey was supported by a competitive Scholarship Award, highlighting her academic excellence. Dr. Rostom also received the Top Oral Communication Award for her impactful presentations and the Young Research Fellow Distinction for her exceptional poster contributions at SCT’s events. These accolades underscore her innovation, dedication, and influence in advancing scientific research.

🔬Research Focus:

Dr. Rostom’s research spans medicinal chemistry, synthetic biology, and molecular biology. She specializes in designing novel cyclocoumarol derivatives, focusing on dual COX-2 inhibitors with anticancer properties. Her expertise extends to synthetic chemistry, developing compounds with pharmacological relevance. Molecular biology techniques, including RT-qPCR, ELISA, confocal microscopy, and cell culture, are central to her work. Her master’s research delved into reproductive biology, investigating smoking’s effects on male fertility. Presently, she focuses on autoimmune diseases, designing therapies for myositis while leveraging bioinformatics for in silico compound development. Her interdisciplinary approach aims to bridge laboratory research with clinical applications.

Publication Top Notes:

    • “Fishing antioxidant 4-hydroxycoumarin derivatives: synthesis, characterization, and in vitro assessments”
    • “Coumarins derivatives and inflammation: Review of their effects on the inflammatory signaling pathways”
      • Citations: 34 citations

 

 

 

 

 

 

Prof. Ahmed elhenawy | Medicinal Chemistry |Best Researcher Award

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Prof. Ahmed elhenawy | Medicinal Chemistry | Best Researcher Award

Prof. Ahmed elhenawy, Azhar unveristy, Egypt

Prof. Ahmed Abd El-Emonam El-Said El-Henawy is a distinguished Egyptian chemist, born on December 23, 1978, in Hellwan, Egypt. With an h-index of 22 and 126 publications, he is a prominent figure in organic chemistry, particularly in peptide synthesis and drug development. Currently, he serves as an Assistant Professor at Albaha University, KSA, and as a Professor at Al-Azhar University, Egypt. With extensive teaching experience, he has guided numerous undergraduate and postgraduate students in organic chemistry. His contributions to research and academia reflect a commitment to advancing knowledge in chemical sciences, emphasizing innovative approaches to synthesizing biologically active compounds.

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Summary of Suitability for Award:

Prof. Ahmed Abd El-Emonam El-Said El-Henawy is an exemplary candidate for the “Best Researcher Awards,” primarily due to his substantial contributions to the field of organic chemistry and his commitment to advancing scientific knowledge. With an h-index of 22 and 126 publications, his research output demonstrates a high level of impact and relevance within the academic community. His specialization in peptide synthesis, particularly the development of novel amino acid derivatives with potential antimicrobial and anticancer activities, showcases his innovative approach to addressing critical health challenges.

🎓Education:

Prof. El-Henawy completed his Bachelor’s degree in Special Chemistry at Al-Azhar University in 2000. He pursued a Master’s degree in Organic Chemistry, focusing on amino acids and proteins, graduating in 2005. His doctoral research, completed in 2008, investigated new amino acid derivatives with expected biological activities. He has held various academic positions at Al-Azhar University, including Demonstrator, Assistant Lecturer, Lecturer, Associate Professor, and Professor, contributing to the department’s growth and the education of future chemists. Additionally, he has been involved in teaching at Albaha University since 2012, where he continues to inspire students through comprehensive organic chemistry courses.

🏢Work Experience:

Prof. El-Henawy has over two decades of experience in academia and research. He began his career as a Demonstrator at Al-Azhar University in 2002 and progressed to the role of Assistant Lecturer in 2005. He became a Lecturer in 2008, then an Associate Professor in 2014, and is currently a Professor. His research focuses on the synthesis of dipeptides and related compounds with potential antimicrobial and anticancer activities. He has developed expertise in various laboratory techniques, including multistep synthesis, chromatographic purification, and spectroscopic analysis. Prof. El-Henawy has supervised numerous M.Sc. and Ph.D. theses in peptide synthesis, reflecting his dedication to nurturing the next generation of chemists. His collaborative research has been presented at international conferences and published in reputable journals.

🏅Awards:

Prof. El-Henawy has received recognition for his contributions to the field of chemistry and education. His research has led to significant advancements in organic chemistry, particularly in synthesizing biologically active compounds. While specific awards are not listed, his h-index of 22 and 126 publications highlight his impact and credibility within the scientific community. His involvement in international conferences showcases his commitment to sharing knowledge and fostering collaboration among researchers. By mentoring students and guiding their research endeavors, he has played a vital role in shaping future chemists. Prof. El-Henawy’s dedication to teaching and research has earned him respect among colleagues and students alike, establishing him as a key figure in the chemistry department at both Al-Azhar University and Albaha University

🔬Research Focus:

Prof. El-Henawy’s research primarily focuses on organic chemistry, emphasizing peptide synthesis and the development of novel amino acid derivatives. His work includes synthesizing dipeptides, tri-, tetra-, and pentapeptides with antimicrobial properties. He has also explored new sulfonamide derivatives as potential antimicrobial agents and synthesized 2-amino-1,3,4-thiadiazole derivatives with anticancer potential. His research incorporates advanced laboratory techniques, such as multistep synthesis and chromatographic isolation. Prof. El-Henawy utilizes various spectroscopic methods to elucidate the structures of synthesized compounds, contributing to the understanding of their biological activities. His commitment to pharmacological research is evident in projects funded by Albaha University, focusing on the pharmacokinetics and toxicodynamics of pharmaceutical compounds. Through his innovative research, Prof. El-Henawy aims to discover new therapeutic agents that address critical health challenges.

Publication Top Notes:

  • Title: Exploring the anti-diabetic activity of benzimidazole containing Schiff base derivatives: In vitro α-amylase, α-glucosidase inhibitions and in silico studies
  • Title: Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking, dynamics, MM-GBSA …
  • Title: Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
  • Title: Flurbiprofen clubbed schiff’s base derivatives as potent anticancer agents: In Vitro and In Silico approach towards breast cancer
  • Title: Synthesis, anticancer, α-glucosidase inhibition, molecular docking and dynamics studies of hydrazone-Schiff bases bearing polyhydroquinoline scaffold: In vitro and in silico

 

 

 

Marina Vesovic | Pharmaceutical chemistry | Medical Chemistry Award

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Prof Dr. Marina Vesovic | Pharmaceutical chemistry | Medical Chemistry Award

Professor at Faculty of Medical Sciences Serbia

Prof. Dr. Marina Vesovic is an Associate Professor in the Department of Pharmacy at the Faculty of Medical Sciences, University of Kragujevac. Elected to her current position in June 2023, she specializes in Pharmaceutical Chemistry. Her research focuses on the synthesis, modeling, and evaluation of organic compounds and metal complexes, particularly in relation to their anti-inflammatory, antioxidant, and cytotoxic activities.

Author Metrics

Scopus Profile

  • Citations: 13 citations across 12 documents
  • h-index: 2 (This index measures both the productivity and citation impact of the researcher’s publications.)

Research Documents and Impact

Number of Documents: 5
Citations by Document: Reflects the impact and relevance of each published work.

Education

Prof. Vesovic’s educational background includes advanced studies in Pharmaceutical Chemistry, which laid the foundation for her expertise and ongoing research in this field. Specific details about her degrees and institutions are not provided, but her role as an associate professor indicates a strong academic background.

Research Focus

Her research centers on medicinal chemistry, pharmaceutical chemistry, and bioinorganic chemistry. She investigates the synthesis and biological activities of organic compounds and metal complexes, focusing on their therapeutic potential and biochemical interactions.

Professional Journey

Prof. Vesovic’s professional journey includes her recent promotion to Associate Professor in 2023, her leadership in various research projects, and her active participation in advancing the field of pharmaceutical chemistry. She has mentored graduate students and contributed to significant research projects in her domain.

Honors & Awards

The bio does not mention specific honors or awards, but Prof. Vesovic’s significant contributions to research and education, including her role in various high-impact projects and publications, highlight her esteemed position in her field.

Publications Noted & Contributions

Prof. Vesovic has published extensively, with 18 articles in M20 category journals, 32 in M30, 10 in M50, and 17 in M60. Her notable contributions include a textbook titled “Pharmaceutical Chemistry 1 – Selected Chapters” and numerous research articles detailing her work on pharmaceutical compounds.

Indomethacin Derivatives as Potential Anticancer Agents – Daybreak of New Epoch

Authors: Gogic, A., Vesovic, M., Nedeljkovic, N., Zdravkovic, N., Zivanovic, A.
Journal: ChemistrySelect, 2024, 9(30), e202402050
Citations: 0
Summary: This article explores the potential of indomethacin derivatives as anticancer agents. It presents a detailed study on the synthesis and evaluation of these derivatives, focusing on their anticancer properties. The research aims to offer new insights into drug development for cancer treatment.

Design of Vonoprazan Pyrazole Derivatives as Potential Reversible Inhibitors of Gastric Proton Pump: An In Silico Molecular Docking Study

Authors: Karović, M., Nikolić, B., Nedeljković, N., Vesović, M., Nikolić, M.
Journal: Acta Facultatis Medicae Naissensis, 2024, 41(1), pp. 53–79
Citations: 0
Summary: This article employs in silico molecular docking to design pyrazole derivatives of vonoprazan as potential reversible inhibitors of the gastric proton pump. It offers a computational approach to drug design, aiming to enhance the efficacy of treatments for gastric acid-related disorders.

Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen

Authors: Nedeljković, N., Nikolić, M., Čanović, P., Vujić, Z., Dobričić, V.
Journal: Pharmaceutics, 2024, 16(1), 1
Citations: 3
Summary: This paper details the synthesis and characterization of novel thiourea derivatives of naproxen, focusing on their anti-inflammatory and cytotoxic activities. The study provides valuable data on these compounds’ potential therapeutic applications and biological effectiveness.

Investigation of the Interaction Between S-Isoalkyl Derivatives of Thiosalicylic Acid and Human Serum Albumin

Authors: Vesović, M., Jelić, R., Nikolić, M., Kljun, J., Tomović, D.
Journal: Journal of Biomolecular Structure and Dynamics, 2024
Citations: 0
Summary: This research investigates how S-isoalkyl derivatives of thiosalicylic acid interact with human serum albumin. The study highlights the binding specificity and potential implications for drug delivery and design.

Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen

Authors: Nedeljković, N., Dobričić, V., Bošković, J., Vujić, Z., Nikolić, M.
Journal: Pharmaceuticals, 2023, 16(5), 666
Citations: 10
Summary: This article focuses on the synthesis and anti-inflammatory activity of new thiourea derivatives of naproxen. It provides insights into how these new compounds might improve treatment for inflammatory conditions and their potential benefits over existing drugs.

Research Timeline

Ongoing projects include investigations into the synthesis and biological properties of organic and metal complex compounds, with a focus on anti-inflammatory and antioxidant activities. Her recent research efforts span from 2023 to the present, continuing to build on her previous work.

Collaborations and Projects

Prof. Vesovic is involved in several research projects funded by the Ministry of Education, Science, and Technological Development. Her projects include the synthesis and characterization of new drug derivatives, and she is a member of professional societies such as the Serbian Crystallographic Society and the Serbian Society for Immunology, Molecular Oncology, and Regenerative Medicine.

Strengths of Prof. Dr. Marina Vesovic for the Medical Chemistry Award

  1. Research Contributions: Prof. Vesovic’s research focuses on significant areas of pharmaceutical chemistry, including anti-inflammatory, antioxidant, and cytotoxic activities. Her work on indomethacin derivatives, pyrazole derivatives of vonoprazan, and novel thiourea derivatives of naproxen illustrates her commitment to advancing drug development and therapeutic applications.
  2. Publication Record: Her extensive publication record, including articles in high-impact journals like ChemistrySelect and Pharmaceutics, demonstrates a strong and active research presence. Notably, her contributions to understanding drug mechanisms and interactions highlight her expertise.
  3. Innovative Research: Prof. Vesovic’s research employs cutting-edge methods such as in silico molecular docking and detailed biochemical investigations. Her studies into drug interactions with human serum albumin and the development of new drug derivatives show a forward-thinking approach to pharmaceutical chemistry.
  4. Educational and Professional Impact: As an Associate Professor at the Faculty of Medical Sciences, University of Kragujevac, Prof. Vesovic plays a vital role in educating the next generation of pharmaceutical chemists. Her leadership in research projects and mentorship of graduate students underscores her influence in the field.
  5. Active Research Projects: Her ongoing research projects funded by reputable organizations and her involvement in professional societies demonstrate her dedication and engagement with the broader scientific community. These efforts contribute to both theoretical and practical advancements in pharmaceutical chemistry.

Areas for Improvement

  1. Citation Impact: Despite a solid publication record, Prof. Vesovic’s citation metrics are relatively modest. Increasing the visibility and impact of her research could involve strategic collaborations and high-profile publications to enhance citation counts.
  2. Research Visibility: While her research is highly relevant, increasing its visibility through conference presentations, media engagement, or collaborative projects with international researchers could further elevate her profile in the field.
  3. Grant Funding: Securing additional research funding or collaborating on larger, multi-institutional grants could provide more resources for her projects and expand the scope of her research.
  4. Publication Diversity: Expanding the range of journals where her work is published, including higher-impact journals or interdisciplinary platforms, might improve both the reach and influence of her research.
  5. Award and Recognition: Gaining recognition through prestigious awards or honors could further validate her contributions to the field. Actively pursuing such accolades or nominations could enhance her professional standing.

Conclusion

Prof. Dr. Marina Vesovic is a promising candidate for the Medical Chemistry Award due to her significant research contributions, extensive publication record, and innovative approaches to drug development. Her work demonstrates a deep understanding of pharmaceutical chemistry and its applications in medicine. By addressing areas such as increasing research visibility and enhancing citation impact, she could further strengthen her candidacy and contribute even more significantly to the field of pharmaceutical chemistry.